Highlights from the 2014 LA Auto Show

Stem Cells

Researchers have developed coated magnetic nanoparticles that can be used to help regenera...

When a bone is severely broken in the human body, or a bone-fused prosthesis is implanted, a bone graft is also often required to ensure a solid mechanical repair. However, a graft that removes bone from another area of the body can be a painful and invasive procedure, and the mechanical stimulation required for continued bone regeneration in post-operative therapy becomes problematic if a patient is severely immobilized. To address these problems, researchers have discovered that coating magnetic nanoparticles with proteins and then directing them magnetically to the site of the injury can help stimulate stem cells to regenerate bone.  Read More

Encapsulated toxin-producing stem cells (in blue) help kill brain tumor cells in the tumor...

When it comes to new tumor-fighting treatments, it’s often as much about location, location, location as it is the actual drug interaction. Cytoxin-producing stem cells produced by scientists at Harvard University lodge at the site of brain tumor removal to continually attack remaining tumor cells. As an alternative to drug treatments that can be invasive or ineffective, the researchers saw promising results against glioblastomas, which hold the dubious distinction of being the most common and most fatal brain cancer.  Read More

Human stem cell-derived beta cells formed islet-like clusters and made insulin when transp...

Stem cell researchers at Harvard University have devised a method for creating large quantities of human insulin-producing beta cells, which could soon lead to a cure for type 1 diabetes as well as a new treatment for type 2 diabetes. The cells are currently being trialled in animals and non-human primates with hopes human trials could take place in the near future..  Read More

Stem cells in rats and mice have been mobilized to form new muscle tissue 'in situ' (i.e.,...

Muscle lost through traumatic injury, congenital defect, or tumor ablation may soon be regenerated from within. A team of researchers at Wake Forest Baptist Medical Center has shown how stem cells in the body of mice and rats can be mobilized to form new muscle in damaged regions.  Read More

London researchers have revealed that stroke patients in a pilot study all showed improvem...

A pilot study undertaken by researchers from Imperial College Healthcare NHS Trust and Imperial College London has shown promise in rapid treatment of serious strokes. The study, the first of its kind published in the UK, treated patients using stem cells from bone marrow.  Read More

Functional human platelets (the orange starfish-like things in the picture) could one day ...

Scientists have already successfully coaxed stem cells into becoming red blood cells, which could be used to create "man-made" blood for transfusion. Red blood cells, however, aren't the only component of human blood. Now, researchers at Harvard-affiliated Brigham and Women’s Hospital have also created functional human platelets, using a bioreactor that simulates the medium in which blood cells are naturally produced – bone marrow.  Read More

Researchers regrow corneas using human stem cells (Photo: Shutterstock)

Medical researchers working with human stem cells have discovered a way to improve regrowth of corneal tissue in the human eye. Using a molecule known as ABCB5 to act as an identifying marker for rare limbal stem cells, the researchers were able to use antibodies to detect ABCB5 on stem cells in tissue from donated human eyes and use them to regrow anatomically correct, fully functional human corneas in mice.  Read More

Rod photoreceptors (in green) within a 'mini retina' derived from human iPS cells in the l...

The eye is often compared to a camera, but although its basic design is as simple as an old-fashioned box Brownie, its detailed structure is more complex than the most advanced electronics. This means that, unlike simpler organs, studies of retinal disease rely heavily on animal studies, and treating such illnesses is extremely difficult. One ray of hope in the field comes from researchers at Johns Hopkins, who have constructed a functioning segment of a human retina out of stem cells that is able to respond to light.  Read More

New research indicates that it may one day be possible for us to regrow teeth ... with som...

Ranking among the X-Men probably isn't all that it's cracked up to be, but who wouldn't want their uncanny ability to regenerate lost bone or tissue? New research into tooth repair and stem cell biology, from a cross-institution team led by David Mooney of Harvard's Wyss Institute, may bring such regeneration one step closer to reality – or at the very least, give us hope that we can throw away those nasty dentures.  Read More

Disabled mice regained the ability to walk less than two weeks after receiving human neura...

When scientists at the University of Utah injected human stem cells into mice disabled by a condition similar to multiple sclerosis, they expected the cells to be rejected by the animals' bodies. It turned out that the cells were indeed rejected, but not before they got the mice walking again. The unexpected finding could have major implications for human MS sufferers.  Read More

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