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Obesity

EnteroMedics VBLOC vagal blocking therapy is delivered via a pacemaker-like device called ...

EnteroMedics' Maestro System has become the first obesity device to be approved by the United States Food and Drug Administration in ten years. The device, which the company compares to a pacemaker, is designed to block signals in the nervous system to reduce feelings of hunger.  Read More

Research say that a new enzyme has been shown to offer prevention or a cure for obese mice...

Research carried out at the University of California and the University of Barcelona has uncovered an enzyme inhibitor found to prevent and reverse the effects of diabetes in obese mice. In addition to discovering a potential form of treatment for the disease, scientists say the study has shone new light on healthy properties of fatty acids.  Read More

Lead scientist Ronald Evans consuming an 'imaginary meal,' of the type that fexaramine cou...

When we eat a meal, our body detects that we've consumed calories and responds by burning fat in order to make room for them. The catch for the weight-conscious is that if we don't burn off those newly-arrived calories, they just end up being stored as more fat. For people with metabolic disorders or other conditions, exercise just isn't enough to keep that from happening. Soon, however, a newly-developed drug could help. It triggers the body's "burning fat to make space for calories" response, even when the patient hasn't eaten anything.  Read More

Scientists have identified a protein that regulates fat levels in worms and could do the s...

Research around how the body's fat levels are regulated and ways in which they might be manipulated has uncovered numerous potential fat switches. The latest is a particular protein that has long been known to regulate protein synthesis and has now been demonstrated to also control fat levels in worms. This has lead researchers at the University of Southern California (USC) to believe that the version found in the human body could provide a new target for fat-fighting pharmaceuticals.  Read More

A single molecule made by combining three hormones has been found to effectively cure obes...

In 2012, we covered work led by Professor Richard DiMarchi that showed linking two hormones into a single molecule held promise as a treatment for obesity. DiMarchi followed this up last year by combining the properties of two endocrine hormones to provide an effective treatment for both obesity and adult-onset diabetes. Continuing in this vein, DiMarchi has now co-led a study whereby obesity and diabetes were effectively cured in lab animals by adding a third hormone to the molecular mix.  Read More

Inulin-propionate ester (IPE) could be added to foods, causing them to suppress the consum...

When we get the feeling of "being full," it's because our gut has released hormones that tell our brain to stop being hungry. It would seem to follow, therefore, that people who overeat might benefit from producing greater amounts of those hormones. Well, that's just what an experimental new food additive is claimed to cause the body to do.  Read More

Researchers have developed a system to uncover compounds capable of turning 'bad' white fa...

Researchers at Harvard University say they have identified two chemical compounds that could replace "bad" fat cells in the human body with healthy fat-burning cells, in what may be the first step toward the development of an effective medical treatment – which could even take the form of a pill – to help control weight gain.  Read More

A genetically-inherited microbe naturally found in the gut that is more common in thin peo...

A new study has determined that not only are bacteria naturally found in the gut involved in obesity, diabetes, and cardiovascular disease, but they are genetically inherited. Researchers at King's College London and Cornell University identified a highly-heritable bacterial family that is more common in individuals with low body weight and that could pave the way for genetics-based personalized probiotic therapies for obesity-related diseases.  Read More

The mutant gene SKN-1 found in the worm Caenorhabditis elegant has been shown to negate we...

Sure, foods that are high in sugar are often the most tempting, but that sugar rush can come at a weighty cost. A new study conducted at the University of South Carolina has suggested that this may not need be the case. Researchers have identified a gene that can dictate how these foods are processed, potentially suppressing the weight problems that go hand-in-hand with unhealthy eating habits.  Read More

Researchers have modified a strain of E. coli to produce a lipid compound called NAPE in t...

Researchers at Vanderbilt University in Nashville, Tennessee have raised hopes for the possibility of developing of a probiotic to treat obesity and other chronic diseases. The team inhibited weight gain, insulin resistance and various other negative health effects of a high-fat diet in mice by modifying bacteria to produce a therapeutic compound in the gut.  Read More

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