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Mice

A compound commonly found in fruit and vegetables, including apples, grapes and strawberri...

Alzheimer's disease represents the most common form of dementia, with the early stages of the disease generally characterized with short term memory loss and learning difficulties that increase in severity as the patient progresses in age. Scientists at the Salk Institute for Biological Studies, California, have discovered that with regular treatments of the antioxidant fisetin, they were able to prevent memory loss in mice with genetic mutations linked to Alzheimer's.  Read More

New research has provided 'strong hope' of finding a drug to combat Alzheimer’s (Image: Sh...

A team of researchers at Yale University has completed a molecular model for Alzheimer's disease by identifying a protein that plays a key role in its onset. Promisingly, the study showed that when the activity of this protein is blocked by an existing drug, mice engineered as models for human AD recover their memories.  Read More

HIH researchers have found that suppressing the expression of a single gene in mice extend...

Researchers at the National Institutes of Health have found that suppressing the expression of a single gene in mice extends their average lifespan by about 20 percent – the equivalent of humans living an average of 95 years. While modification of the so-called mTOR gene may not lead to the fountain of youth, further study could open up a path to keeping us healthier and more alert in our old age.  Read More

The Microsoft Sculpt Ergonomic keyboard and mouse

Microsoft has unveiled a new Sculpt range of keyboards and mice with ergonomic features designed to improve comfort over long periods. The new accessories offer a number of useful features, such as dedicated Windows buttons and a split spacebar design, and are the result of a global survey carried out by the company.  Read More

An study led by Indiana University has found that linking two hormones into a single molec...

With recent studies finding that – for the first time – more people now die from obesity-related illnesses like heart attacks and strokes than malnutrition, scientists have been tackling the fat problem. One of the latest breakthroughs in this field comes from the University of Indiana where researchers have found that combining two hormones into a single molecule could lead to improved treatments for medical conditions such as obesity and type 2 diabetes.  Read More

Researchers at Stanford University have successfully alleviated PTSD in sleeping mice (Pho...

Though often associated with exposure to war, Post-Traumatic Stress Disorder (PTSD), is a severe anxiety disorder which can arise following exposure to any event which has caused psychological trauma. Those who suffer from PTSD are often subjected to re-living the source of their despair through nightmares and flashbacks, and current treatment results in only occasional success. However, researchers at Stanford University appear to have alleviated PTSD in mice while the rodents slept, by using a new technique which may prove applicable for humans in the future.  Read More

Researchers have reportedly restored near-normal vision to blind mice, using a prosthesis ...

Retinal prostheses such as the Argus II, Bio-Retina and the Retina Implant AG microchip all work – more or less – by stimulating the retina’s ganglion cells with light-induced electrical signals. The images produced in the patient’s visual cortex tend to be quite rudimentary, however. This is partially because the rate at which the signals are sent isn’t the same as the rate of neural impulses normally produced by a retina. Now, researchers have deciphered the neural code used by mouse ganglion cells, and used it to create a prosthesis that reportedly restores normal vision to blind mice. They have additionally deciphered the neural code of monkeys, which is close to that used by humans, so a device for use by blind people could also be on the way.  Read More

Rapamycin, a bacterial product first discovered in a soil sample from Easter Island, has b...

Rapamycin, a bacterial product first discovered in a soil sample from Easter Island – also known as Rapa Nui, hence the name – is an immunosuppressant drug used to prevent rejection in organ transplants that has now been found to enhance learning and memory in young and old mice alike. Researchers at the School of Medicine at The University of Texas (UT) Health Science Center San Antonio made the discovery while looking for a way to prevent the decline in cognitive skills that comes with age.  Read More

Scientists have developed a method of duplicating an individual person's unique immune sys...

Because everyone’s immune system is different, it’s impossible to predict with absolute certainty how any given person will react to a specific medication. In the not-too-distant future, however, at-risk patients may get their own custom-altered mouse, with an immune system that’s a copy of their own. Medications could be tried out on the mouse first, and if it showed no adverse reactions, then the person could receive them. If the person had an autoimmune disease, the mouse could also provide valuable insight into its treatment. A team led by Columbia University Medical Center’s Dr. Megan Sykes has recently developed a method of creating just such a “personalized immune mouse.”  Read More

Image of a mouse with implanted tumors before and after receiving photoimmunotherapy (PIT)...

Besides surgery, chemotherapy and radiation are the foundation of modern day cancer treatment. Although effective, these therapies often have debilitating and damaging side effects. But scientists at the National Cancer Institute in Bethesda, Maryland have been experimenting with a new form of therapy using infrared light to kill cancer cells and shrink tumors without damaging healthy tissue.  Read More

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