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Malaria

Blocking the pathway used by the malaria parasite to export proteins could pave the way fo...

While the World Health Organization (WHO) says increased preventative measures have seen malaria mortality rates fall by 42 percent since 2000, the disease still claims more than half a million lives each year. A study carried out by a team of Melbourne-based researchers has shown that blocking a gateway used by the parasite to export proteins ultimately causes it to die off, opening the door for the development of new types of anti-malarial drugs.  Read More

The Foldscope is made mostly of cardstock, and can be shipped flat-packed

According to the World Health Organization, there were approximately 207 million cases of malaria worldwide in 2012, 627,000 of which proved fatal. Unfortunately, the disease most often occurs in developing nations, where diagnostic equipment may not be available. This means that doctors can't determine the particular strain of malaria from which a patient is suffering, and thus don't know which medication will work best. Manu Prakash, an assistant professor of bioengineering at the Stanford School of Medicine, hopes to change that ... using his disposable folding paper microscope.  Read More

NTU Prof Peter Preiser and scientist Dr Annie Gao

A new discovery by scientists from Singapore’s Nanyang Technological University (NTU) holds promise for the development of a Malaria vaccine. The result of five years research, the breakthrough is based on the ability to block the invasion of red blood cells by the deadly parasite.  Read More

New trial vaccine against malaria shows promise (Image: CDC/Jim Gathany)

A vaccine against malaria currently being developed in the US offers new hope to fight the infectious disease that enters the body through a mosquito bite. According to the World Health Organization, malaria killed 660,000 people in 2010. The intravenous vaccine currently being developed by Sanaria and the National Institute of Allergy and Infectious Diseases (NIAID) has produced promising results in volunteers who received a high dose the vaccine.  Read More

Anopheles mosquito after taking a snack (Photo: US Center for Disease Control and Preventi...

A small company in the U.K. is developing an affordable, hand-held device that will not only diagnose malaria in the field, but will also read DNA markers that suggest which antimalarial drugs will be most effective for treatment. If fielded, such a device could help alleviate the 200+ million cases of malaria per year, as well as prevent some of the nearly one million deaths associated with malarial illness.  Read More

LG's 'Anti-Mosquito' air conditioner uses ultrasonic waves to repel malaria-transmitting m...

While promising vaccines and genetically-engineered mosquitoes are providing hope in the fight against malaria, it currently remains a major and potentially life-threatening problem in tropical and subtropical regions around the world. These regions are also hot and sticky, making LG's introduction of an air conditioner that it claims actively repels mosquitoes as it keeps the house cool a seemingly obvious blending of technologies.  Read More

Scientists have created genetically-modified mosquitoes that are incapable of spreading ma...

Last year, Prof. Anthony James announced that he and his colleagues had genetically altered Aedes aegypti mosquitoes in a fashion that could drastically reduce their populations. In a nutshell, the altered genes cause the female mosquitoes to be born without wings – this makes it rather difficult for them to go foraging for blood, and turns them into easy prey for almost any predator. The non-biting males are born with wings, and subsequently go off and mate with unmodified females, passing the modified genes along to their offspring. Now, James has done some more genetic engineering, to create mosquitoes that can’t spread malaria.  Read More

Engineered microvessels can form bends and T-junctions, like this one. The blue dots are t...

A team of bioengineers at the University of Washington has developed the first structure for growing small human blood vessels in the laboratory. The vessels behave remarkably like those in a living human and offer a better and much more modular approach to studying blood-related diseases, testing drugs and, one day, growing human tissues for transplant.  Read More

A female mosquito probes for a meal (Photo: Shutterstock)

With malaria still responsible for millions of untimely deaths in more than 90 countries each year, the search for effective antimalarial drugs, vaccines and mosquito repellents continues to heat up. Recently, researchers at the University of Illinois (UI), led by chemistry professor Eric Oldfield, found that a chemically-altered form of a commonly prescribed osteoporosis drug can easily enter red blood cells and dispatch malaria parasites without harming the host (in this case, a mouse). That's potentially huge news for the countless thousands who continue to suffer from this recurrent, debilitating and all-too-often fatal disease.  Read More

Anopheles Gambiae mosquito

You're in the middle of a great chat with friends on a warm summer night, and then "ouch" a mosquito interrupts your conversation with a bite on your forearm. Experimental physicist Szabolcs Marka hopes to make this occurrence a thing of the past, but in this case it's not aerosol spray or roll-on-repellant keeping the bugs at bay, it's a wall of light.  Read More

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