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Fat cells

Scientists have identified a protein that regulates fat levels in worms and could do the s...

Research around how the body's fat levels are regulated and ways in which they might be manipulated has uncovered numerous potential fat switches. The latest is a particular protein that has long been known to regulate protein synthesis and has now been demonstrated to also control fat levels in worms. This has lead researchers at the University of Southern California (USC) to believe that the version found in the human body could provide a new target for fat-fighting pharmaceuticals.  Read More

Researchers have developed a system to uncover compounds capable of turning 'bad' white fa...

Researchers at Harvard University say they have identified two chemical compounds that could replace "bad" fat cells in the human body with healthy fat-burning cells, in what may be the first step toward the development of an effective medical treatment – which could even take the form of a pill – to help control weight gain.  Read More

A new study has found that changes in ambient temperature can influence the concentration ...

The discovery that lowering your body temperature leads to an increase in a certain type of "good" fat might have some ditching the diet books and shedding a layer of clothing instead. A study conducted at the National Institute of Health (NIH) in Washington has demonstrated that changes in ambient temperature affects brown fat levels in humans, pointing to potential treatment options for the weight-wary and sufferers of diabetes.  Read More

There's gold in that thar belly – or at least there might soon be, if a new form of liposu...

Liposuction may be a popular method of instant body fat reduction, but it certainly isn't perfect. Patients can experience bruising, there can be lumps that have to be addressed with a second procedure, plus things other than fat cells – such as connective tissue and nerves – can inadvertently also get removed. Two researchers, however, are developing what could be a better form of liposuction, that involves first using injected gold microparticles to melt the fat.  Read More

Viagra has been found to convert white fat cells into beige fat cells, potentially aiding ...

Researchers from the University of Bonn have treated mice with Viagra and discovered that the drug converts white fat cells (those unwanted denizens of the belly and similar swollen regions) into beige fat cells. Instead of storing excess energy, these recently discovered beige fat cells burn the energy from ingested food and convert it to heat. Viagra also appears (at least in mice) to decrease the risk of other complications caused by obesity.  Read More

Injecting a tiny capsule into the abdomens of mice resulted in a reduction in abdominal fa...

We’ve seen a number of encouraging developments in recent times related to research into turning calorie-storing white fat cells into heat-generating brown fat cells as a potential weapon in the fight against obesity and related diseases, such as diabetes. The latest news comes out of Ohio State University where researchers have reduced the amount of belly fat in mice by 20 percent by injecting a tiny capsule containing brown fat cells into their abdomens.  Read More

The identification of the mechanism that causes white fat cells to become brown fat cells ...

Earlier this year, a team from UC San Francisco reported on the discovery that a class of commonly prescribed type-2 diabetes drugs, called TZDs (thiazolidinediones, such as Actos and Avandia), promoted the conversion of energy-storing white fat cells into energy-burning brown fat cells. Now researchers at Columbia University Medical Center (CUMC) have identified the mechanism that causes this change to take place, potentially leading to new techniques to treat obesity and type-2 diabetes.  Read More

A newly-discovered third type of fat cell could be a target in the fight against obesity (...

The existence of two different types of fat – or adipose tissue – in mammals has long been known: white fat, which stores calories and in excess results in obesity, and brown fat, which burns calories to generate energy and heat. Now scientists at the Dana-Farber Cancer Institute have confirmed the existence of a third, genetically distinct type of fat called “beige fat,” which they say is a potential therapeutic target for treating obesity.  Read More

Scientists have discovered a protein that activates brown fat (pictured) in mice (Image: T...

For most of us fighting the battle of the bulge, fat is an enemy that must be reigned in to a healthier – and less noticeable – level. But there are actually two types of fat – or adipose tissue – found in mammals, white and brown. While white fat stores calories and is the culprit behind love handles, brown fat’s primary function is to generate heat to keep the body warm through the burning of fats in a process known as thermogenesis. Therefore, the ability to activate brown fat in the body could provide a means to fight obesity and keep the weight off. Now scientists have discovered a protein that could allow them to do just that.  Read More

Specially-treated fat cells may one day lead to weight loss

Though it's long been known that there are two forms of fat or adipose tissue, white, which stores calories, and brown, which burns them for energy and warmth, figuring out how to safely create more of the desirable brown type has remained elusive. In an ideal world, there'd simply be a switch one could flip to convert white fat into brown and obesity would eventually become a thing of the past. Now, UC San Francisco (UCSF) Diabetes Center brown fat researcher Shingo Kajimura and his team have made a discovery that leads them to believe they've found that switch and one day, it just may lead to the long-sought solution for human obesity.  Read More

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