Highlights from Interbike 2014

Disease

A rendering of the nanometer-scale DNA clamp, that recognizes genetic mutations more stron...

Scientists have developed a special DNA clamp to act as a diagnostic nano machine. It's capable of detecting genetic mutations responsible for causing cancers, hemophilia, sickle cell anemia and other diseases, more efficiently than existing techniques. Not only can the clamp be used to develop more advanced screening tests, but it could also help create more efficient DNA-based nano machines for targeted drug delivery.  Read More

NTU Prof Peter Preiser and scientist Dr Annie Gao

A new discovery by scientists from Singapore’s Nanyang Technological University (NTU) holds promise for the development of a Malaria vaccine. The result of five years research, the breakthrough is based on the ability to block the invasion of red blood cells by the deadly parasite.  Read More

Researchers at the University of Huddersfield are developing a breath test for lung cancer...

With lung cancer survival rates greatly improved by early detection, we've seen a number of efforts to develop a better way to detect the disease in its early stages. Various breath test devices have been developed by a number of companies around the world, and now a team from the University of Huddersfield in the UK plans to trial such a device to identify lung cancer in pharmacies.  Read More

Drugs called 'pharmacoperones' can fix the problems that occur when proteins 'misfold'

Proteins adopt their functional three-dimensional structure by the folding of a linear chain of amino acids. Gene mutation can cause this folding process to go awry, resulting in "misfolded" proteins that are inactive or, in worse cases, exhibit modified or toxic functionality. This is the cause of a wide range of diseases, but researchers have developed a technique that fixes these misfolded proteins, allowing them to perform their intended function, thereby providing a potential cure for a number of diseases.  Read More

A newly developed nanoparticle may signal the end of injections for treatment of some comm...

Most of us would swallow a pill before being poked by a needle, yet sufferers of chronic illnesses are regularly required to administer their medicine intravenously. A team of researchers from MIT and Brigham and Women's Hospital (BWH) has developed a new type of nanoparticle that could afford patients the choice – potentially making uncomfortable injections a thing of the past in the treatment of a range of chronic diseases.  Read More

The tenofovir disoproxil fumarate intravaginal ring – or TDF-IVR, for short

According to UNAIDS, a member of the United Nations Development Group, 58 percent of people living with HIV/AIDS in sub-Saharan Africa are women. Although preventative drugs and condoms do block the transmission of HIV, neither are always practical, available or affordable in developing nations. Help could be on its way, however, in the form of an anti-HIV intravaginal ring that is worn continuously for up to 30 days.  Read More

Scientists at the Oregon Health and Science University have announced a positive step towa...

A very promising vaccine candidate for HIV/AIDS has shown the ability to completely clear the simian immunodeficiency virus (SIV), a very aggressive form of HIV that leads to AIDS in monkeys. Developed at the Vaccine and Gene Therapy Institute at the Oregon Health and Science University (OHSU), the vaccine proved successful in about fifty percent of the subjects tested and could lead to a human vaccine preventing the onset of HIV/AIDS and even cure patients currently on anti-retroviral drugs.  Read More

The Fraxinus game (Image: The Sainsbury Laboratory)

Playing video games and feeling virtuous may seem almost like a contradiction in terms, but the Sainsbury Laboratory in Norwich, UK has turned gaming into a way to advance science and help protect the environment. The Fraxinus game is a Facebook app that uses player participation to figure out the structure of a fungus genome, as part of a crowdsourcing effort to combat a disease that threatens Britain and Europe’s ash trees.  Read More

Initial prototypes of the 'blood pressure watch' with the strap made from piezo-resistive ...

Blood pressure is one of the main vital signs, measuring the pressure of the blood upon the walls of blood vessels as it is pumped around the body by the heart. High blood pressure, or hypertension, places increased stress on the heart and can be an indicator of other potentially fatal health problems, such as stroke, heart attack, and heart failure. Most people will have had their blood pressure tested using a sphygmomanometer on a visit to the doctor, but a new wristband device is set to provide a more convenient and continuous way to keep a watch for signs of trouble.  Read More

Scanadu has turned to crowdfunding website Indiegogo to bring what it calls 'the first med...

Scanadu has turned to crowd-funding website Indiegogo to bring what it calls "the first medical tricorder," its Scout diagnostic device, to market. Though expected to ship to home users in March 2014, Scanadu highlights that until the Scout is approved by the FDA, it should not be thought of as a medical device. Instead, backers are described as testers who will help to gather the data to gain that approval.  Read More

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