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Diabetes

Iron nanoparticles (blue), tethered to the ion channel seen (red) by a protein (green) hav...

Sufferers of type 1 diabetes regularly need to inject themselves with insulin in order to regulate levels of sugar in their blood, a process that is invasive and requires particular care. But a new study conducted at the Rensselaer Polytechnic Institute suggests that more comfortable treatment methods may not be all that far away, with scientists remotely manipulating insulin production in mice using electromagnetic waves.  Read More

A single molecule made by combining three hormones has been found to effectively cure obes...

In 2012, we covered work led by Professor Richard DiMarchi that showed linking two hormones into a single molecule held promise as a treatment for obesity. DiMarchi followed this up last year by combining the properties of two endocrine hormones to provide an effective treatment for both obesity and adult-onset diabetes. Continuing in this vein, DiMarchi has now co-led a study whereby obesity and diabetes were effectively cured in lab animals by adding a third hormone to the molecular mix.  Read More

Clinical trials are set to begin in 2015 on the potential of a common blood pressure drug ...

A study at the University of Alabama at Birmingham (UAB) has shown that verapamil, a drug widely used to treat high blood pressure, irregular heartbeat and migraine headaches, is able to completely reverse diabetes in animal models. The UAB team will now move onto clinical trials to see if the same results are repeated in humans.  Read More

Diabetic foot ulcers may soon be treated with a new drug delivered via a transdermal patch...

When someone has diabetes, foot injuries such as ulcers can take a long time to heal. Not only does this cause diabetics prolonged discomfort, but it can even lead to amputation. Help may be on the way, however, in the form of a drug that's delivered through a skin patch.  Read More

Human stem cell-derived beta cells formed islet-like clusters and made insulin when transp...

Stem cell researchers at Harvard University have devised a method for creating large quantities of human insulin-producing beta cells, which could soon lead to a cure for type 1 diabetes as well as a new treatment for type 2 diabetes. The cells are currently being trialled in animals and non-human primates with hopes human trials could take place in the near future..  Read More

A sample of the hydrogel turns from blue to green to red, as it takes up glucose

Thanks to a new color-changing hydrogel, there may soon be a more reliable way of continuously monitoring the blood glucose levels of both diabetics and hospital patients. If incorporated into a device such as an implanted pump, it could automatically trigger the release of insulin into the bloodstream as needed.  Read More

Orgenesis' approach involves harvesting the patient's own liver cells and converting them ...

When pancreatic islet allo-transplantation therapy was first introduced, it provided hope for countless diabetics tired of daily insulin injections. While the technology has delivered on much of its promise, Tel Aviv-based regenerative medicine firm Orgenesis is currently developing a treatment of its own, that it claims addresses much of the shortcomings of islet therapy. In a nutshell, its approach involves converting the patient’s own liver cells into cells that produce insulin.  Read More

A new system developed at Princeton University allows diabetics to check blood glucose lev...

Finger-prick tests to monitor blood glucose levels can be the bane of a diabetic's life. In a move that could put an end to such tests in the future, researchers at Princeton University have developed a non-invasive way to test blood glucose levels using a laser.  Read More

Researchers at the Salk Institute have found that the FGF1 protein shows promise for the d...

There are numerous research efforts underway to develop new treatments and improve the lives of people suffering type 2 diabetes, whose ranks have increased dramatically in recent decades due in large part to the so-called obesity epidemic. A new generation of safer and more effective diabetes drugs could be in the offing with researchers at the Salk Institute discovering that when mice with diet-induced diabetes were given a single injection of a protein, their blood sugar levels were restored to a healthy range for more than two days.  Read More

A prototype of the pupillometer

Diabetic autonomic neuropathy is a condition that can occur in both type 1 and type 2 diabetics, compromising the autonomic nerves that control the gastrointestinal system, the heart and other vital organs. Among other things, it can cause arrhythmias, fainting, incontinence and an increased risk of bacterial infections. Thanks to a device being developed in Taiwan, however, it may soon be possible to detect the condition earlier, thus limiting its effects.  Read More

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