A microscope image of a zebrafish retina immunolabeled for ultraviolet cones (magenta) and rods (green). (Photo: Florida State Associate Professor James Fadool and Alverez-Delfin)
Since the eyes of the zebrafish contain a mosaic of light-sensitive cells whose structure and functions are nearly identical to those of human eyes, their study may help understand the progression of disease and find more effective treatments for blindness. A study of the retinal development of zebrafish larvae by scientists from Florida State Universityand has identified a genetic switch that should shed new light on these molecular mechanisms and, consequently, provide much needed insight on inherited retinal diseases in humans.
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