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Wyss Institute

Rod-like devices are injected just beneath the skin and self-assemble into 3D scaffolds (I...

Scientists have had some success activating the body's immune system to take the fight to cancer and other diseases, a process known as immunotherapy. Now, a new method developed by researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University could advance this form of treatment even further. The technique involves the injection of biomaterials that assemble into 3D scaffolds inside the body to accommodate huge amounts of immune cells, a process that could trigger an attack on deadly infections ranging from HIV to cancer to Ebola.  Read More

The insoles use vibrations to help their wearers detect tactile stimuli in the soles of th...

Falls are the leading cause of death by injury amongst seniors, and those falls are in turn typically caused by poor balance or an irregular gait. Taking things back yet another step, problems with balance and gait are often caused by diminished sensation in the feet. Now, however, a new study indicates that subtly-buzzing insoles may help seniors regain some of that lost sensation, and thus be less likely to fall down.  Read More

Researchers have used a DNA brick self-assembly method to build 32 different crystal struc...

The very same building blocks that make us have been successfully programmed to form 32 differently-shaped crystal structures. The structures feature a precisely-defined depth and a variety of sophisticated 3D nanoscale attributes, thereby laying further foundations for the use of DNA to revolutionize nanotechnology.  Read More

Glass slides dipped in blood to demonstrate the effectiveness of the TLP coating. with blo...

Our bodies have evolved to be pretty good at dealing with incursions by foreign objects and bacteria. Usually, that's a positive thing, but it can spell trouble for medical devices, such as replacement joints, cardiac implants and dialysis machines, which increase the risk of blood clots and bacterial infection. Now researchers at Harvard University have developed a surface coating that smooths the way for medical devices to do their job inside the human body.  Read More

A human airway muscle-on-a-chip developed at Harvard's Wyss Institute could help in the se...

Unfortunately for asthma sufferers and those looking to develop new treatments to help them, animal models traditionally used to test potential new drugs don't always mimic human responses. Joining lungs and guts, scientists at Harvard's Wyss Institute have now developed a human airway muscle-on-a-chip that could help in the search for new treatments for asthma. The device accurately mimics the way smooth muscle contracts in the human airway, both under normal circumstances and when exposed to asthma triggers.  Read More

Emulate's lung-on-chip, seen here, is lined with human lung and blood vessel cells

The search for more efficient tests of pharmaceuticals without animal models is taking a stride forward, with a new technology being developed in the US called Organs-on-Chips. The new miniature platform and software, which mimic the mechanical and molecular characteristics of human organs, were developed by bioengineers from the Wyss Institute for Biologically Inspired Engineering at Harvard University.  Read More

A self-folding mobile prototype developed by researchers at MIT and Harvard (Photo: Harvar...

An origami-inspired robot that self-assembles and then scuttles away under its own power has been revealed by researchers from Harvard University and MIT. Still in the experimental stage, the prototype is able to transform itself from a flat structure into a moving, functional machine in around four minutes before scrambling away under its own power at a speed of about 2 in (5 cm) per second.  Read More

New research indicates that it may one day be possible for us to regrow teeth ... with som...

Ranking among the X-Men probably isn't all that it's cracked up to be, but who wouldn't want their uncanny ability to regenerate lost bone or tissue? New research into tooth repair and stem cell biology, from a cross-institution team led by David Mooney of Harvard's Wyss Institute, may bring such regeneration one step closer to reality – or at the very least, give us hope that we can throw away those nasty dentures.  Read More

The team constructed a lipid-coated nanodevice that survived the mouse immune system due t...

Researchers from Harvard University's Wyss Institute for Biologically Inspired Engineering have developed a cloaked DNA nanodevice capable of evading the body's immune defenses. The design was inspired by real world viruses and could be used to diagnose cancer and better target treatments to specific areas of tissue.  Read More

Illustrations of a human heart doing the left ventricular twist (left), and the Harvard mo...

When you think of a beating heart, you probably just picture it flexing in and out, sort of like a rubber ball being squeezed by an invisible hand. In fact, though, its motion is more similar to that of a dish rag being wrung out, with the top of the organ twisting in a clockwise direction while the bottom contracts counterclockwise. It's known as the left ventricular twist, and scientists have now replicated it using artificial muscles. The research could lead to better-functioning cardiac implants, among other things.  Read More

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