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Wyss Institute

Emulate's lung-on-chip, seen here, is lined with human lung and blood vessel cells

The search for more efficient tests of pharmaceuticals without animal models is taking a stride forward, with a new technology being developed in the US called Organs-on-Chips. The new miniature platform and software, which mimic the mechanical and molecular characteristics of human organs, were developed by bioengineers from the Wyss Institute for Biologically Inspired Engineering at Harvard University.  Read More

A self-folding mobile prototype developed by researchers at MIT and Harvard (Photo: Harvar...

An origami-inspired robot that self-assembles and then scuttles away under its own power has been revealed by researchers from Harvard University and MIT. Still in the experimental stage, the prototype is able to transform itself from a flat structure into a moving, functional machine in around four minutes before scrambling away under its own power at a speed of about 2 in (5 cm) per second.  Read More

New research indicates that it may one day be possible for us to regrow teeth ... with som...

Ranking among the X-Men probably isn't all that it's cracked up to be, but who wouldn't want their uncanny ability to regenerate lost bone or tissue? New research into tooth repair and stem cell biology, from a cross-institution team led by David Mooney of Harvard's Wyss Institute, may bring such regeneration one step closer to reality – or at the very least, give us hope that we can throw away those nasty dentures.  Read More

The team constructed a lipid-coated nanodevice that survived the mouse immune system due t...

Researchers from Harvard University's Wyss Institute for Biologically Inspired Engineering have developed a cloaked DNA nanodevice capable of evading the body's immune defenses. The design was inspired by real world viruses and could be used to diagnose cancer and better target treatments to specific areas of tissue.  Read More

Illustrations of a human heart doing the left ventricular twist (left), and the Harvard mo...

When you think of a beating heart, you probably just picture it flexing in and out, sort of like a rubber ball being squeezed by an invisible hand. In fact, though, its motion is more similar to that of a dish rag being wrung out, with the top of the organ twisting in a clockwise direction while the bottom contracts counterclockwise. It's known as the left ventricular twist, and scientists have now replicated it using artificial muscles. The research could lead to better-functioning cardiac implants, among other things.  Read More

The researchers used three specially developed inks that borrow biological properties from...

The notion of 3D printed biological tissue holds all kinds of possibilities for drug testing and the reparation of damaged cells, though replicating the complexities of human tissue in a lab presents some very big challenges. A new bioprinting method developed by researchers from the Wyss Institute for Biologically Inspired Engineering at Harvard University has enabled the creation of tissue constructs with small blood vessels and multiple cell types, marking important progress toward the printing of living tissue.  Read More

The humidity-driven flexing of a spore-covered piece of latex rubber (right) drives the mo...

Ozgur Sahin believes that water evaporation is the largest power source in nature. In an effort to demonstrate the potential of this untapped resource, Sahin and his fellow researchers have created prototype electrical generators with rubber sheets that move in response to changes in humidity thanks to a coating of bacterial spores.  Read More

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