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Maintaining sugar levels in a brain protein known as tau could slow or prevent Alzheimer's...

We’ve reported on numerous different approaches by scientists looking to tackle Alzheimer’s disease. While some, such as the anticancer drug bexarotene and a compound known as J147, show great promise, there is still no approved treatment to slow the disease’s progression. The latest promising candidate for a treatment comes from Canada’s Simon Fraser University (SFU), where a team has concluded that ensuring that sugar levels in a brain protein known as tau are maintained could slow or prevent the fatal disease.  Read More

The programmable DNA nanorobot developed by Wyss Institute researchers is shaped like a ba...

We've seen various experimental approaches that aim to increase the efficacy of chemotherapy while also reducing its damaging side effects by specifically targeting cancer cells. The latest encouraging development comes from Harvard's Wyss Institute for Biologically Inspired Engineering where researchers have created a barrel-like robotic device made from DNA that could carry molecular instructions into specific cells and tell them to self-destruct. Because the DNA-based device could be programmed to target a variety of cells, it could be used to treat a range of diseases in addition to providing hope in the fight against cancer.  Read More

Scientists are reporting success in the first human trial of a chip-based implant that del...

Much as anyone with a medical condition wants to get better, it can often be difficult to get patients to stick to their medication regimens. This is particularly true for patients who are required to give themselves injections – a time-consuming and unpleasant procedure that it’s easy to “forget” to do. Scientists from MIT and Massachusetts-based company MicroCHIPS Inc., however, have come up with what could be a solution. Yesterday, they announced success in the first clinical trial of an implantable chip-based device, that automatically delivered regular doses of medication to osteoporosis sufferers.  Read More

RESPeRATE is a device that is designed to lower blood pressure by getting its users to bre...

People suffering from hypertension (also known as high blood pressure) are typically advised to switch to a healthier diet, get more exercise and lose weight, plus they are often put on a combination of several medications. As of today, UK residents are now also able to get a prescription for what is definitely a different type of treatment – a system known as RESPeRATE. It monitors the patient’s breathing and uses sound to guide them into taking longer, slower breaths, thus relaxing their bodies. According to its makers, multiple clinical trials have shown that it causes significant, lasting reductions in blood pressure.  Read More

Engineers and researchers at UT Arlington aim to develop a biomask that could revolutioniz...

Engineers and researchers at the University of Texas, Arlington in collaboration with military medical institutions aim to develop a mask that would use mechanical, electrical and biological components to speed up the healing process following severe facial burns. The flexible polymer face mold is to be fitted with sensors for the monitoring of the healing process. If necessary, embedded components would selectively administer the appropriate pharmaceuticals to the right section of the wound. The aim of the Biomask project is not only to prevent further disfigurement, but also to facilitate facial tissue regeneration in injured soldiers.  Read More

A new type of endoscope is said to be able to remove gallstones (pictured), reducing the n...

When someone has gallstones, treatment typically involves the removal of their gallbladder. This is usually done laparoscopically, in a procedure known as a cholecystectomy. A group of scientists from the Second People's Hospital of Panyu District and Central South University in China, however, have created an endoscope that they say is able to locate and remove gallstones while leaving the gallbladder intact.  Read More

Left: Natural control mechanism blocks the enzyme's zinc active site Right: Novel antibody...

Researchers of Israel's Weizmann Institute of Science have achieved a significant new development which may have far reaching implications for the treatment of autoimmune diseases which attack the body's own tissue by mistake. The scientists have managed to convince the immune systems of mice to instead attack an enzyme significant to the body's autoimmune process known as matrix metallopeptidase 9 (MMP9).  Read More

Postdoctoral fellow Guoming Sun (left) and Sharon Gerecht, an assistant professor of chemi...

Third-degree burns typically require very complex treatment, and leave nasty scars once they've healed. Researchers at Johns Hopkins University, however, are reporting success at treating such burns on lab mice, using a new type of hydrogel that grows new skin (as opposed to scar tissue) over burn sites. The gel contains no drugs or biological components - it's made mainly from water and dissolved dextran, which is a sugar-like polymer.  Read More

Image of a mouse with implanted tumors before and after receiving photoimmunotherapy (PIT)...

Besides surgery, chemotherapy and radiation are the foundation of modern day cancer treatment. Although effective, these therapies often have debilitating and damaging side effects. But scientists at the National Cancer Institute in Bethesda, Maryland have been experimenting with a new form of therapy using infrared light to kill cancer cells and shrink tumors without damaging healthy tissue.  Read More

We’ve previously looked at the development of cancer treatments that deliver drugs directly into cancer cells before releasing their chemotherapeutic payload to reduce the damage done to healthy cells. But a new protein “switch” approach developed by researchers at Johns Hopkins University changes the game again by instructing cancer cells to produce their own cancer medication, causing the cancer cells to self-destruct while sparing healthy tissue.  Read More

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