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Stem Cells

A previously hairless mouse following an implantation of bioengineered hair follicles recr...

Researchers lead by Professor Takashi Tsuji from the Tokyo University of Science have successfully induced the natural hair growth and loss cycle in previously hairless mice. They have achieved this feat through the implantation of bioengineered hair follicles recreated from adult-tissue derived stem cells. While these results offer new hope for curing baldness, the work has broader implications, demonstrating the potential of using adult somatic stem cells for the bioengineering of organs for regenerative therapies.  Read More

Scientists have used genetically engineered stem cells to seek out and kill HIV-infected c...

Although there is currently no cure for HIV, the body does already contain cells that fight the virus – the problem is, there just aren’t enough of them to completely get rid of it. In 2009, scientists at UCLA performed a proof-of-concept experiment, in which they were able to grow these CD8 cytotoxic T lymphocytes (better known as infection-fighting “T cells”) from genetically engineered human stem cells. Now, in a subsequent study, they have demonstrated that these engineered cells can seek out and kill HIV-infected cells in a living organism.  Read More

Image of the induced neural stem cells created by reprogramming skin cells (Photo: MPI for...

Researchers at the Max Planck Institute for Molecular Biomedicine in Münster, Germany, have broken new ground by reprogramming skin cells from mice into neurons without regressing the cells through a pluripotent stage. The skin cells were reprogrammed directly into multipotent neuronal stem cells - that is, into cells which could only turn into new neurons. This procedure avoids the significant risk that pluripotent stem cells, which can grow into any type of tissue, may accidentally form tumors rather than the desired replacement tissue.  Read More

Using a modified HP DeskJet 500 printer, researchers at Clemson University have discovered...

Old inkjet printers are an important tool for bioprinting. Recently, researchers from Clemson University discovered that inkjet bioprinting disrupts the membranes of the cells being printed, leaving them open to having proteins inserted ... and opening up new avenues of research in the field.  Read More

Physicians at the University of Wisconsin-Madison have succeeded in growing human retinal ...

Among the primary causes of adult-onset blindness are degenerative diseases of the retina, such as macular degeneration and retinitis pigmentosa. While some treatments have been developed that slow down the rate of degeneration, the clinical situation is still generally unsatisfactory. But if you could grow a new retina, transplant might be a possible cure. Now new hope is springing up from a research project at the University of Wisconsin-Madison in which scientists have succeeded in growing human retinal tissue from stem cells.  Read More

Scientists have developed a method of duplicating an individual person's unique immune sys...

Because everyone’s immune system is different, it’s impossible to predict with absolute certainty how any given person will react to a specific medication. In the not-too-distant future, however, at-risk patients may get their own custom-altered mouse, with an immune system that’s a copy of their own. Medications could be tried out on the mouse first, and if it showed no adverse reactions, then the person could receive them. If the person had an autoimmune disease, the mouse could also provide valuable insight into its treatment. A team led by Columbia University Medical Center’s Dr. Megan Sykes has recently developed a method of creating just such a “personalized immune mouse.”  Read More

A new material known as 'fracture putty' could be used to help broken bones heal much more...

Anyone who has ever broken a bone knows that while receiving the injury itself is quite unpleasant, being laid up for several weeks to even a few months afterwards is also no picnic. Help may be on the way, however. The U.S. Department of Defense is funding a study, to develop fast bone-healing treatments that could be used on soldiers, along with civilians and even animals. Already, scientists have gotten promising results in laboratory tests, using something they call “fracture putty.”  Read More

UCLA's Dr. Steven Schwartz (center) transplanting specialized cells derived from human emb...

UCLA researchers are reporting a milestone in the therapeutic use of stem cells after two legally blind patients who received transplants of specialized retinal cells derived from human embryonic stem cells reported a modest improvement in their vision. Monitoring of the patients’ progress over a four month period also found no safety concerns, signs of rejection or abnormal cell growth. The researchers are claiming that the success of the procedure could pave the way for a new therapy to treat eye diseases.  Read More

Chimeric monkeys Roku, Hex and Chimero (not pictured) are the first three primates ever to...

Scientists have reached a major milestone in the field of stem cell research. A team at the Oregon National Primate Research Center (ONPRC) say their work has led to the first successful birth of three chimeric monkeys - monkeys developed from stem cells taken from two separate embryos.  Read More

A cross-section of engineered cartilage tissue, which initially incorporated fast-degradin...

Injuries involving torn or degraded joint cartilage can be very debilitating, especially since that cartilage is incapable of healing itself, past a certain point. It's not surprising, therefore, that numerous scientists have been working on ways of either growing replacement cartilage outside of the body, or helping the body to regrow it internally. Just a few of the efforts have included things like stem cell-seeded bandages, bioactive gel, tissue scaffolds, and nanoscale stem cell-carrying balls. Now, researchers from Cleveland's Case Western Reserve University have announced something else that shows promise - sheets of mesenchymal (bone and cartilage-forming) stem cells, permeated with tiny beads filled with the growth factor beta-1.  Read More

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