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Stem Cells

A human liver (Image: Department of Histology, Jagiellonian University Medical College)

Researching liver disorders is extremely difficult because liver cells (hepatocytes) cannot be grown in the laboratory. However, researchers at the University of Cambridge have now managed to create diseased liver cells from a small sample of human skin. The research shows that stem cells can be used to model a diverse range of inherited disorders and paves the way for new liver disease research and possible cell-based therapy.  Read More

Rows of human embryonic stem cells, grown on the new surface

Stem cells have been touted as the potential key to treating ailments ranging from Parkinson’s disease and multiple sclerosis to spinal cord injuries, to name just a few. That’s because they can be made into any type of cell that’s needed - they’re essentially the plasticine of the cell world. The problem that scientists have encountered is the difficulty in growing them. For one thing, it’s hard to grow enough of them to perform large-scale experiments. For another, most of the materials upon which the stem cells are grown contain cells or proteins from mouse embryos, which stimulate cell growth but would probably also cause an immune reaction if injected into a human recipient. Researchers from the Massachusetts Institute of Technology (MIT), however, have just announced the creation of a new growing surface that does away with both of these limitations.  Read More

A new breakthrough in cell regeneration could lead to the repair of damaged hearts (Image ...

Heart disease remains one the biggest killers in the Western world. When a heart attack or heart failure occurs, permanent damage often results, destroying live cells and leaving the patient with irreversible scarring. Now scientists at the Gladstone Institute of Cardiovascular Disease (GICD) have discovered a new technique to create healthy beating heart cells from structural cells, opening up the possibility of regenerating damaged hearts.  Read More

The scaffold is built out of a flexible, biocompatible material with pores that support th...

Although medical advances over recent years have seen the majority of people surviving heart attacks, the damage done to the heart muscle is irreversible. As a result, most patients eventually succumb to congestive heart failure, the most common cause of death in developed countries. Stem cells offer hope for achieving what the human body can’t do: mending broken hearts. Now researchers have built a scaffold that supports the growth and integration of stem cell-derived cardiac muscles cells. The scaffold supports the growth of cardiac cells in the lab and encourages blood vessel growth in living animals.  Read More

A technique that combines nanotechnology with adult stem cells appears to destroy atherosc...

A combination of nanotechnology and adult stem cells has been shown to destroy arterial plaque (atherosclerosis) in the heart of pigs. Pigs that received stem cells also showed signs of new blood vessel growth and restoration of artery function according to the study reported at the American Heart Association's Basic Cardiovascular Sciences 2010 Scientific Sessions – Technological and Conceptual Advances in Cardiovascular Disease.  Read More

Fibroblasts growing on Dr. Brian Amsden's polymer fiber

A Canadian researcher is hoping that within ten years, people will be able to regrow tendons, spinal cords or heart valves lost to injury or disease. Dr. Brian Amsden, a chemical engineering professor from Queen’s University, is developing a technique wherein cells from a patient’s body would be placed on a polymer prosthetic that stimulates cell growth. After the cells had established themselves sufficiently, the prosthetic would be implanted in the patient’s body. The polymer would then biodegrade, leaving behind nothing but the patient’s own tissue.  Read More

First retina created from stem cells could help millions

In another world first in the fight against degenerative eye disorders, scientists from the Universtiy of California, Irvine, have created an eight-layer early-stage retina from human embryonic stem cells. Not only is this the world's first three-dimensional complex tissue structure to be made from stem cells, but it also marks the first step toward the development of transplant-ready retinas to treat eye disorders affecting millions.  Read More

Dr. Mao's microchannelled scaffold

Conventional dental implants are typically screwed into the patient’s jaw bone, require visits to several types of clinicians, take two to six months to heal and are still subject to failure. Not exactly an ideal solution to missing teeth. A professor of dental medicine at Columbia University Medical Center, however, has devised a technique wherein implants could be grown in the empty tooth socket, right inside the patient’s mouth.  Read More

Hair cells like these have been successfully recreated in a petri dish (Photo: CC)

It’s become an accepted fact of life that people tend to lose much of their hearing as they get old. This is because our hair cells, the cells in our ears which allow us to hear, cannot regenerate - we’re born with 30,000 per ear, but once they die off or get damaged, they’re gone for good. Stefan Heller, a professor of otolaryngology (ear, nose and throat stuff) at Stanford University, wants to change that. To that end, he recently succeeded in creating mouse hair cells in a petri dish. Could an end to deafness be far behind?  Read More

New bio-active nanomaterial enables humans to grow new cartilage

Sport is tough on the body, and one of the major health risks from being active is permanent damage to cartilage around the joints. Humans are unable to regenerate cartilage once they are adults and often have to live with little relief from painful joints or osteoarthritis, but researchers at Northwestern University are the first to design a bio-active nanomaterial that promotes the growth of new cartilage in vivo and without the use of expensive growth factors. Good new sports fans...  Read More

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