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Stem Cells

Scientists have developed a method of duplicating an individual person's unique immune sys...

Because everyone’s immune system is different, it’s impossible to predict with absolute certainty how any given person will react to a specific medication. In the not-too-distant future, however, at-risk patients may get their own custom-altered mouse, with an immune system that’s a copy of their own. Medications could be tried out on the mouse first, and if it showed no adverse reactions, then the person could receive them. If the person had an autoimmune disease, the mouse could also provide valuable insight into its treatment. A team led by Columbia University Medical Center’s Dr. Megan Sykes has recently developed a method of creating just such a “personalized immune mouse.”  Read More

A new material known as 'fracture putty' could be used to help broken bones heal much more...

Anyone who has ever broken a bone knows that while receiving the injury itself is quite unpleasant, being laid up for several weeks to even a few months afterwards is also no picnic. Help may be on the way, however. The U.S. Department of Defense is funding a study, to develop fast bone-healing treatments that could be used on soldiers, along with civilians and even animals. Already, scientists have gotten promising results in laboratory tests, using something they call “fracture putty.”  Read More

UCLA's Dr. Steven Schwartz (center) transplanting specialized cells derived from human emb...

UCLA researchers are reporting a milestone in the therapeutic use of stem cells after two legally blind patients who received transplants of specialized retinal cells derived from human embryonic stem cells reported a modest improvement in their vision. Monitoring of the patients’ progress over a four month period also found no safety concerns, signs of rejection or abnormal cell growth. The researchers are claiming that the success of the procedure could pave the way for a new therapy to treat eye diseases.  Read More

Chimeric monkeys Roku, Hex and Chimero (not pictured) are the first three primates ever to...

Scientists have reached a major milestone in the field of stem cell research. A team at the Oregon National Primate Research Center (ONPRC) say their work has led to the first successful birth of three chimeric monkeys - monkeys developed from stem cells taken from two separate embryos.  Read More

A cross-section of engineered cartilage tissue, which initially incorporated fast-degradin...

Injuries involving torn or degraded joint cartilage can be very debilitating, especially since that cartilage is incapable of healing itself, past a certain point. It's not surprising, therefore, that numerous scientists have been working on ways of either growing replacement cartilage outside of the body, or helping the body to regrow it internally. Just a few of the efforts have included things like stem cell-seeded bandages, bioactive gel, tissue scaffolds, and nanoscale stem cell-carrying balls. Now, researchers from Cleveland's Case Western Reserve University have announced something else that shows promise - sheets of mesenchymal (bone and cartilage-forming) stem cells, permeated with tiny beads filled with the growth factor beta-1.  Read More

Scientists have reversed the aging process in human adult stem cells, which are in turn re...

By now, most people are probably aware of the therapeutic value of stem cells, as they can become any other type of cell in the human body. One of their main duties, in fact, is to replace those other cells as they degrade. Once people reach an advanced age, however, even the stem cells themselves start to get old and nonfunctional - when the cells that are supposed to replace the other cells can't do their job anymore, age-related tissue problems start occurring. A team of researchers from the Buck Institute for Research on Aging in collaboration with the Georgia Institute of Technology, however, may be on the way to solving that problem. They have succeeded in reversing the aging process in human adult stem cells.  Read More

Scientists at Stanford University have created heart cells that contract when exposed to l...

Working their way towards energy-efficient pacemakers that use light pulses to control the beating of the heart, scientists at New York's Stony Brook University recently developed optogenetic heart tissue – it contracts when exposed to light. More specifically, they took donor cells that had been modified to respond to light, and coupled them to conventional heart cells. A team from California’s Stanford University, however, has now created actual optogenetic heart cells.  Read More

A discovery by Yale researchers could lead to new treatments for baldness (Image: Tumblewe...

In news that offers hope to millions of chrome-domes everywhere – yours truly included – Yale researchers have made a discovery that could lead to new treatments for baldness. While men with male pattern baldness still have stem cells in follicle roots, they need signals from within the skin to grow hair. Until now, the source of those signals that trigger hair growth has been unclear, but the Yale researchers claim to have now discovered it.  Read More

A new type of stem-cell-seeded bandage, designed to heal torn meniscal cartilage such as  ...

Every year, approximately 1.7 million people in the U.S. and Europe tear a meniscus – children and athletes are especially prone to such injuries. But first, just what is a meniscus? It’s one of two pieces of cartilage located inside each knee, that provide a cushion between the tibia and the femur. While smaller tears can heal on their own, larger tears often require a partial or complete removal of the meniscus. Within several years, this can result in the early onset of osteoarthritis. Recently, a new type of stem cell-seeded bandage, developed at the University of Bristol, has been approved for a clinical trial on meniscal tears. It may greatly reduce the need for menisectomies.  Read More

Scientists from have generated pluripotent stem cells from horses for the first time (Phot...

For the first time ever, scientists from the University of Montreal and Mount Sinai Hospital have generated pluripotent stem cells from horses. Pluripotency refers to a cell's ability to become any of the various other types of cells found within the body, and the ability to be able to grow such cells in a laboratory setting has great implications for the field of regenerative medicine. Not only does this latest accomplishment potentially mean big things for sick or injured horses, but it could also pave the way for lab-based human stem cell treatments.  Read More

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