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Stem Cells


— Medical

Human blood platelets grown in bone marrow-replicating bioreactor

Scientists have already successfully coaxed stem cells into becoming red blood cells, which could be used to create "man-made" blood for transfusion. Red blood cells, however, aren't the only component of human blood. Now, researchers at Harvard-affiliated Brigham and Women’s Hospital have also created functional human platelets, using a bioreactor that simulates the medium in which blood cells are naturally produced – bone marrow. Read More
— Medical

Corneas regrown using human stem cells

Medical researchers working with human stem cells have discovered a way to improve regrowth of corneal tissue in the human eye. Using a molecule known as ABCB5 to act as an identifying marker for rare limbal stem cells, the researchers were able to use antibodies to detect ABCB5 on stem cells in tissue from donated human eyes and use them to regrow anatomically correct, fully functional human corneas in mice. Read More
— Science

Three-dimensional light-sensitive retinal tissue grown in lab

The eye is often compared to a camera, but although its basic design is as simple as an old-fashioned box Brownie, its detailed structure is more complex than the most advanced electronics. This means that, unlike simpler organs, studies of retinal disease rely heavily on animal studies, and treating such illnesses is extremely difficult. One ray of hope in the field comes from researchers at Johns Hopkins, who have constructed a functioning segment of a human retina out of stem cells that is able to respond to light. Read More
— Medical

Low-power laser triggers stem cells to repair teeth

Ranking among the X-Men probably isn't all that it's cracked up to be, but who wouldn't want their uncanny ability to regenerate lost bone or tissue? New research into tooth repair and stem cell biology, from a cross-institution team led by David Mooney of Harvard's Wyss Institute, may bring such regeneration one step closer to reality – or at the very least, give us hope that we can throw away those nasty dentures. Read More
— Medical

"Heart disease-on-a-chip" could usher in an age of personalized medicine

When we've previously heard about "organs on a chip," they've been miniature recreations of healthy organs. If they're being used for research into the treatment of health problems, however, then it only makes sense that those "organs" should have something wrong with them. With that in mind, a group of Harvard scientists have created the world's first lab-grown sample of functioning human heart tissue that has a cardiovascular disease. Read More
— Medical

Human stem cells used to repair damaged monkey hearts

In what could mark a significant breakthrough in the treatment of heart disease, researchers at the University of Washington (UW) have successfully repaired damaged tissue in monkey hearts using cells created from human embryonic stem cells. The findings demonstrate an ability to produce these cells on an unprecedented scale and hold great potential for restoring functionally of damaged human hearts. Read More
— Medical

First transfusions of "manufactured" blood planned for 2016

According to the World Health Organization, approximately 107 million blood donations are collected globally every year. Nonetheless, blood is often in short supply – particularly in developing nations. Despite new safeguards, there's also still the risk of incompatibility, or of infections being transmitted from donors to recipients. Charitable organization the Wellcome Trust hopes to address these problems, by developing the ability to manufacture blood outside of the body. Last week, it announced that test subjects should begin receiving transfusions of blood made with lab-grown red blood cells by late 2016. Read More
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