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Stem Cells

Medical

Creation of insulin-releasing cells in a dish offers hope of diabetes therapy

A molecular switch could hold the key to a personalized cell replacement therapy for diabetes. Both Type 1 and Type 2 diabetes are characterized by an inability to produce (or process) insulin, which is required to regulate blood sugar levels. This has been linked to malfunctioning or failing beta cells in the pancreas, but so far scientists have struggled to produce effective replacement cells in the lab. Now a team at Salk Institute believes the problem has been solved.Read More

Medical

Looking to love handles to treat diabetes

If a patient has Type 1 diabetes, then their ability to produce insulin is inhibited, usually by a loss of beta cells in the pancreas. Researchers have been looking at ways to replace the lost population of cells, but the process is difficult, often requiring the patient's immune system to be suppressed in order to be effective. Now, researchers at ETH Zurich have made a big breakthrough, successfully creating functional beta cells using stem cells extracted from the fatty tissue of a 50 year-old patient.Read More

Medical

Humans could get salamander-like tissue regeneration abilities in "a few years"

In what could prove to be a game changer in stem cell therapy, a team led by scientists at the University of New South Wales (UNSW) have discovered a way to reprogram bone and fat cells to become stem cells that can regenerate multiple tissue types. The technique has already proved successful in mice and could be just a few years away from being safely available for regenerating any damaged tissue in humans.Read More

Medical

Mouse gums turned into fully functioning skin

While growing biological components in the lab such as a thymus gland, sperm cells, eye tissue and cartilage are becoming more and more commonplace, thus far, creating fully functioning lab-grown skin has eluded scientists. Previous attempts have produced epithelial cells only, which comprise the outer layer of skin. Now, researchers at Japan's RIKEN Center for Developmental Biology have created skin tissue complete with sebaceous glands as well as hair follicles. They started with mouse gums.Read More

Medical

Neurodegenerative disorders may meet their match with 3D micro-scaffold

Injecting reprogrammed stem cells into the brain to tackle neurodegenerative diseases isn't a new idea, but a new technique might significantly improve the effectiveness of the treatment. A team of sceintists, led by researchers at Rutgers University, has developed and conducted successful animal tests of a three-dimensional polymer micro-scaffold that dramatically improves cell survival rates following transplantation.Read More

Medical

Osteoporosis in mice reversed with single injection of stem cells

Age-related osteoporosis, where the bone structure deteriorates and becomes more vulnerable to fracture, is said to affect more than 200 million people worldwide. Drugs are available to treat or delay the condition, but a cure has remained elusive. Much-needed help may now be on the way, however, with scientists discovering healthy bone structure can be restored in mice with a single injection of stem cells.Read More

Medical

New molecule has stem cells primed for harvesting within the hour

Securing a match for a bone marrow transplant to treat a cancer patient can be difficult enough, but it is not all smooth sailing from that point either. Preparing a donor's stem cells for harvesting involves a lot of time and injections of growth factor to boost stem cell populations ahead of the procedure. But Australian scientists have now unearthed a more direct route, discovering a new molecule that entices an adequate number of stem cells out into the blood stream to make for a much easier, swifter collection.Read More

Medical

​New cataracts treatment restores infants' vision using stem cells

While you might generally associate cataracts with more mature patients, as many as three in every 10,000 children suffer from the condition, which can cause significant vision loss. Now, researchers at the University of California, San Diego (UC San Diego) have tested a new approach to tackling congenital cataracts, turning to existing stem cells to repair the patient lenses post-surgery, restoring vision.
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Medical

Lab-grown eye tissue restores rabbits' vision

In what marks important progress toward a future where defective vision could be treated with lab-grown eyeball components, an international team of scientists has used human stem cells to build layers of eye tissue that was then implanted into rabbits to restore vision. With promising early results, the researchers say their findings could usher in trials where such transplantations are put to the test in humans.Read More

Medical

Lack of stem cells in womb found to be culprit behind recurrent miscarriages

Recurrent miscarriage is defined as having three or more miscarriages in succession and is a heartbreaking event that affects one in 100 women trying to conceive. Scientists are now claiming to have identified a cause, finding a lack of stem cells in the womb lining to be the culprit behind continued failed pregnancies, and aims to begin developing treatments to bolster populations of these cells later in the year.Read More

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