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Scripps Research Institute


— Health and Wellbeing

Nicotine-gobbling enzyme could help smokers quit

By - August 6, 2015 1 Picture

Nicotine replacement therapy, such as pills, gum and patches, can make the road to quitting smoking a little less rocky, but these aren't always effective and a tremendous amount of discipline still plays the major role. A team of US-based researchers has now uncovered an enzyme found in nature they say could greatly improve on the effectiveness of smoking cessation aids, by devouring nicotine in smokers before it can deliver its "reward" to the brain.

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— Health and Wellbeing

New therapy to help addicts put memories of meth use behind them

By - August 5, 2015 1 Picture

Even after a lengthy period of abstinence, putting lingering memories of methamphetamine use to rest is a difficult and often impossible task for former users. Therapies are available to help people stay clean, but for many the lure remains irresistible with incredibly high relapse rates of more than 90 percent, according to the National Institute on Drug Abuse. But a research team is hoping to help addicts stay away from the devastating drug for good by developing a way to safely erase drug-associated memories.

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— Health and Wellbeing

Senolytics: A new class of drugs with the potential to slow the aging process

By - March 10, 2015 1 Picture
It's a cruel irony that when we're young we want to be older, but when we're older we want to be younger. While few would advocate research into ways to make kids grow up faster, there are plenty of efforts underway looking to forestall the rigors of age. The latest cause for hope in this area comes in the form of a new class of drugs called senolytics, which have been shown to dramatically slow the aging process in animal models. Read More
— Medical

New compound that blocks multiple HIV infections shows promise as AIDS vaccine

By - February 19, 2015 1 Picture
A novel vaccine for the AIDS virus may become possible through a new compound proving highly effective in preventing HIV infection. While testing has only been carried out on monkeys so far, the scientists behind the development say that with its ability to block multiple strains of infection at once, the technique has huge potential to one day provide long-lasting protection against the deadly virus. Read More
— Health and Wellbeing

New nicotine vaccine may succeed at treating smoking addiction, where others have failed

By - January 22, 2015 1 Picture
If you're a smoker who's trying to quit, you may recall hearing about vaccines designed to cause the body's immune system to treat nicotine like a foreign invader, producing antibodies that trap and remove it before it's able to reach receptors in the brain. It's a fascinating idea, but according to scientists at California's Scripps Research Institute, a recent high-profile attempt had a major flaw. They claim to have overcome that problem, and are now developing a vaccine of their own that they believe should be more effective. Read More
— Science

New map shows world's seafloor in unprecedented detail

By - October 3, 2014 8 Pictures
Given they aren't covered by oceans, it's maybe not so surprising that we know more about the topography of the Moon and Mars than we do about Earth's ocean depths. But researchers have evened the score at least a little with the creation of a new map of the world's seafloor. Twice as accurate as the previous version produced almost 20 years ago, the new map details thousands of previously uncharted mountains and provides new clues on the formation of the continents. Read More
— Medical

Human stem cell treatment gets mice with MS-like condition walking again

By - May 28, 2014 1 Picture
When scientists at the University of Utah injected human stem cells into mice disabled by a condition similar to multiple sclerosis, they expected the cells to be rejected by the animals' bodies. It turned out that the cells were indeed rejected, but not before they got the mice walking again. The unexpected finding could have major implications for human MS sufferers. Read More
— Medical

Small adhesive patch outperforms traditional tech for detecting arrhythmia

By - January 3, 2014 3 Pictures
Ordinarily, when doctors wish to monitor an ambulatory patient for heartbeat irregularities, they have them wear what is know as a Holter monitor. The device is fairly cumbersome, so it's usually worn for no more than 24 hours. A recent study, however, indicates that the relatively new ZIO Patch provides more accurate readings, while being considerably less obtrusive. Read More
— Health and Wellbeing

New drug mimics the beneficial effects of exercise

By - August 20, 2013 2 Pictures
A drug known as SR9009, which is currently under development at The Scripps Research Institute (TSRI), increases the level of metabolic activity in skeletal muscles of mice. Treated mice become lean, develop larger muscles and can run much longer distances simply by taking SR9009, which mimics the effects of aerobic exercise. If similar effects can be obtained in people, the reversal of obesity, metabolic syndrome, and perhaps Type-II diabetes might be the very welcome result. Read More
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