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Scripps Research Institute

Researchers have developed a drug that is able to prevent multiple strains of HIV from inf...

A novel vaccine for the AIDS virus may become possible through a new compound proving highly effective in preventing HIV infection. While testing has only been carried out on monkeys so far, the scientists behind the development say that with its ability to block multiple strains of infection at once, the technique has huge potential to one day provide long-lasting protection against the deadly virus.  Read More

A vaccine currently in development may be more effective at keeping nicotine molecules fro...

If you're a smoker who's trying to quit, you may recall hearing about vaccines designed to cause the body's immune system to treat nicotine like a foreign invader, producing antibodies that trap and remove it before it's able to reach receptors in the brain. It's a fascinating idea, but according to scientists at California's Scripps Research Institute, a recent high-profile attempt had a major flaw. They claim to have overcome that problem, and are now developing a vaccine of their own that they believe should be more effective.  Read More

A new map of the seafloor is twice as accurate as the previous version (Image: David Sandw...

Given they aren't covered by oceans, it's maybe not so surprising that we know more about the topography of the Moon and Mars than we do about Earth's ocean depths. But researchers have evened the score at least a little with the creation of a new map of the world's seafloor. Twice as accurate as the previous version produced almost 20 years ago, the new map details thousands of previously uncharted mountains and provides new clues on the formation of the continents.  Read More

Disabled mice regained the ability to walk less than two weeks after receiving human neura...

When scientists at the University of Utah injected human stem cells into mice disabled by a condition similar to multiple sclerosis, they expected the cells to be rejected by the animals' bodies. It turned out that the cells were indeed rejected, but not before they got the mice walking again. The unexpected finding could have major implications for human MS sufferers.  Read More

US researchers have engineered a bacterium whose genetic material includes DNA or bases  n...

Scientists at the Scripps Research Institute (TSRI) in California have produced a living bacterium that has a strand of artificial DNA made with chemical “letters” not found in nature or any other organism.  Read More

The ZIO Patch is worn on the chest for up to two weeks (Photo: Scripps)

Ordinarily, when doctors wish to monitor an ambulatory patient for heartbeat irregularities, they have them wear what is know as a Holter monitor. The device is fairly cumbersome, so it's usually worn for no more than 24 hours. A recent study, however, indicates that the relatively new ZIO Patch provides more accurate readings, while being considerably less obtrusive.  Read More

The Scripps Research Institute has developed a drug that duplicates the benefits of exerci...

A drug known as SR9009, which is currently under development at The Scripps Research Institute (TSRI), increases the level of metabolic activity in skeletal muscles of mice. Treated mice become lean, develop larger muscles and can run much longer distances simply by taking SR9009, which mimics the effects of aerobic exercise. If similar effects can be obtained in people, the reversal of obesity, metabolic syndrome, and perhaps Type-II diabetes might be the very welcome result.  Read More

Methamphetamine addicts may one day be able to receive a vaccine, that keeps them from get...

Methamphetamine is one of the most addictive and thus commonly-used street drugs – according to the United Nations Office on Drugs and Crime, there are currently nearly 25 million meth addicts worldwide. Help may be on the way, however. Scientists from The Scripps Research Institute have had success in using a methamphetamine vaccine to block the effects on meth on lab rats.  Read More

New findings have identified a blood test which could predict heart attack or stroke weeks...

Roughly two and a half million Americans suffer a heart attack or a stroke each year. About 20% of these - half a million people - die in the aftermath. The proximate cause for both heart attack and stroke is a blood clot in the wrong place - a blood clot that could be prevented or minimized by anti-clot therapy IF physicians knew that an attack or stroke was expected shortly. New findings from a research study led by Scripps Translational Science Institute (STSI) has identified a new blood test which has the promise of predicting heart attack or stroke weeks prior to their occurrence.  Read More

Researchers have gained partial control of a specific memory and created 'hybrid' memories...

You may remember – pun intended – that earlier in the week we reported on research that may provide an explanation of how memories are stored in the brain. In related news, a team consisting of researchers from the Scripps Research Institute, the University of Oregon and the University of North Carolina has found a way to partially control a specific memory in mice by turning neurons in their brains on and off. Although the research is in its early stages, the scientists say it could lead to a better understanding of how memories form and maybe even provide ways to change people’s thought patterns.  Read More

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