In 2012, we covered work led by Professor Richard DiMarchi that showed linking two hormones into a single molecule held promise as a treatment for obesity. DiMarchi followed this up last year by combining the properties of two endocrine hormones to provide an effective treatment for both obesity and adult-onset diabetes. Continuing in this vein, DiMarchi has now co-led a study whereby obesity and diabetes were effectively cured in lab animals by adding a third hormone to the molecular mix. Read More
Because second- and third-degree burns damage underlying layers of skin, they can take a long time to heal. Such extended healing periods are not only painful to the patient, but increase the risk of infection and scarring. While various medications are available to deal with pain and infection, there is currently no commercial treatment to speed up the rate of healing of burn wounds. Now researchers have developed a nanogel that could fill this hole. Read More
Today at Microsoft’s Think Next symposium in Tel Aviv, Israeli startup StoreDot has demonstrated the prototype of a nanodot-based smartphone battery it claims can fully charge in just under 30 seconds. With the company having plans for mass production, this technology could change the way we interact with portable electronics, and perhaps even help realize the dream of a fast-charging electric car. Read More
A nasal spray containing a specially-developed protein peptide could form the basis for highly-targeted treatment for depression, new research from the Centre for Addiction and Mental Health (CAMH) has shown. The peptide, when delivered in spray from, was found to relieve symptoms of depression, with the lead researcher hopeful of little to no side-effects. Read More
A strong and highly selective instant adhesive inspired by the bacterium Streptococcus pyogenes has been developed by Oxford University researchers. S. pyogenes is a common resident of human throats that is normally kept in check by the body's defenses, but when it gets out of control it can cause diseases ranging from strep throat to toxic shock syndrome or flesh-eating disease. By engineering a protein that is central to S. pyogenes' infectious arsenal, the researchers have developed a new superglue that can't be matched for sticking molecules together and not letting go. Read More
In order to detect the presence of nearby females, the male silk moth utilizes an oily coating on his antennae. Any female pheromone molecules that are in the air will stick to that coating, which then guides them through nanotunnels in the insect's exoskeleton, and ultimately to nerve cells that alert Mr. Moth to the fact that there are ladies in the area. It's a clever enough system that scientists from the University of Michigan have copied it, in hopes of better understanding neurodegenerative diseases such as Alzheimer's. Read More
Confused by that headline? It's simple really – when drugs and medical devices are tested for contamination, a substance called Limulus amebocyte lysate (LAL) is used. LAL is made from the blood cells of horseshoe crabs, which are caught along the U.S. Atlantic coast, drained of 30 percent of their blood, then returned to the water. Although the majority of the crabs survive the process, it has been estimated that at least 30 percent do not. This, in turn, is affecting populations of the red knot, a bird that feeds on horseshoe crab eggs. Now, engineers from Princeton University have discovered that a substance from the skin of the African clawed frog could be used instead of the crab blood – with no harm done to the frog. No word on whether eye of newt or wing of bat would work, too. Read More
While attempting to find a cure for Alzheimer’s disease researchers have discovered a new nanomaterial that can repel dust and water and could provide a self-cleaning coating for windows or solar panels. Unlike similar dust-busting materials that take inspiration from the surface of the lotus leaf, the new material is actually made up of molecules of peptides that “grow” to resemble small forests of grass. The coating also acts as a super-capacitor, thereby having implications for electric cars in that it could provide an energy boost to batteries. Read More
Scientists at UC Santa Barbara have developed a biological mechanism that can act as an entirely new means of drug delivery, carrying with it the potential to make treating illness even more effective. Rather than simply circulating in the bloodstream, the laboratory-developed peptide can deliver nanoparticles directly into tissue. Read More