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Neurological

A new compound, J147, could be the first drug capable of halting the progression of Alzhei...

Anyone who has watched as Alzheimer’s disease robs a friend or family member of their memories and faculties before ultimately claiming their life knows just what a truly horrible disease it is. According to the World Health Organization, it is the fourth leading cause of death in high-income countries and, due to an aging worldwide population, it is predicted to affect one in 85 people worldwide by 2050 – unless a treatment can be found. Scientists at the Salk Institute for Biological Studies have high hopes for a new drug they have developed that has improved memory and prevented brain damage in mice and is a promising candidate for the first drug capable of halting the progression of Alzheimer’s in humans. Read More

The ROBOCAST Project is developing a robotic system for assisting with keyhole neurosurger...

In keyhole neurosurgery, a small “burr hole” is drilled in the patient’s skull, and their brain is then accessed through that hole. The procedure is much less invasive than many other types of brain surgery, and can be used for things such as exploratory endoscopy, biopsies, blood and fluid sampling, cryogenic and electrolytic ablation (tissue removal), and deep brain stimulation. It is used to treat conditions including tumors, hydrocephalus (fluid on the brain), Parkinson's disease, Tourette syndrome, and epilepsy. For a neurosurgeon, however, it can sometimes be extremely exacting work – a slip of even a fraction of a millimeter can cause permanent brain damage. That’s why the European Union’s ROBOCAST (ROBOt and sensors integration for Computer Assisted Surgery and Therapy) Project is developing a robotic system to help out. Read More

Researchers simulate schizophrenia in a computer (Image: Yellowcon)

One of the theories regarding the cause of schizophrenia suggests that, due to an excessive release of dopamine, the brain remembers too many irrelevant things. Schizophrenics are then overwhelmed by the vast amounts of facts, thoughts and memories all crammed together in their heads, and start processing them into conclusions that aren't based in reality. It's called the hyperlearning hypothesis, and researchers at the University of Texas in Austin recently tried to see if they could simulate it – in a computer. Read More

Close neurological ties between reward-processing and pain-processing regions in the brain...

As science continues to unravel the mysteries of ourselves and the world around us at a furious pace, it can sometimes feel like the boffins are proving things that many of us feel we already know or take for granted. This interesting example comes from the Stanford University School of Medicine, where scientists have found that intense feelings of love are as effective at relieving pain as painkillers or even illicit drugs. Read More

An image of a brain's wiring system, acquired using the new software

Utilizing a recently-developed technique called HARDI (High Angular Resolution Diffusion Imaging), researchers at the Eindhoven University of Technology have created a software tool that could reduce the need for exploratory brain surgery. The new technology converts MRI scans of the brain into three-dimensional images, which provide neurologists with a “road map” of the wiring of a patient’s brain. Read More

The Galvanic vestibular stimulation system

There are airplanes and swimming pools that give prospective astronauts a taste of what a zero-gravity environment will feel like, but the sensations that they will feel upon returning from such an environment are also important to simulate. Astronauts coming back to Earth’s gravity often experience disturbances in their vision and neurological function, to the point that they can have trouble walking, keeping their balance, or even safely landing their spacecraft. By utilizing a Galvanic vestibular stimulation (GVS) system, however, scientists can give them a sneak peek of what to expect, so they can better compensate for it when it happens in the field. Read More

StatNet is a single-use EEG which contains electrodes precision aligned in a flexible head...

Traditional electroencephalography (EEG) is time-consuming to set up, must be administered by qualified technologists and relies on reusable electrodes which can leave patients vulnerable to infection. Massachusetts-based HydroDot is aiming to solve these issues and significantly improve the clinical process with StatNet – a flexible, single-use EEG headpiece that offers a simpler, safer, faster and more accurate way to measure electrical activity in the human brain. Read More

Biomedical engineer Brian Lithgow and a model showing the 'tilt chair' and electrode techn...

Central Nervous System (CNS) disorders such as depression, schizophrenia and Attention Deficit Hyperactivity Disorder (ADHD) cost upwards of US$2 trillion globally every year and affect one in four people in their lifetime. At present, diagnosing these conditions relies on an often unreliable process of questions and interviews, which means it can take many years for sufferers to be correctly diagnosed. A new diagnostic technique that measures the patterns of electrical activity in the brain’s vestibular (or balance) system could dramatically fast-track the detection of mental and neurological illnesses. Read More

Jessica Huber,left, and graduate student Meghan Moran demonstrate the technology developed...

The sad reality of Parkinson’s disease is that it indiscriminately affects 1.5 million people in the U.S alone, making it one of the most common degenerative neurological conditions with no known cause or cure. In the effort to make one of Parkinson’s many debilitating symptoms more manageable for sufferers, researchers have developed a new technology to overcome voice and speech impairment by playing a recording of ambient sound resembling the chatter of a busy restaurant. Read More

Professor Markram presents at TEDGlobal 2009

The jury is out on whether scientific and technological advancement will ultimately sound the death-knell for the human race, but such concerns have not stopped Henry Markram, director of the Blue Brain Project, from enthusing about the potential benefits of a synthetic human brain at TED Global 2009. Read More

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