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Mice

Scientists have developed a method of duplicating an individual person's unique immune sys...

Because everyone’s immune system is different, it’s impossible to predict with absolute certainty how any given person will react to a specific medication. In the not-too-distant future, however, at-risk patients may get their own custom-altered mouse, with an immune system that’s a copy of their own. Medications could be tried out on the mouse first, and if it showed no adverse reactions, then the person could receive them. If the person had an autoimmune disease, the mouse could also provide valuable insight into its treatment. A team led by Columbia University Medical Center’s Dr. Megan Sykes has recently developed a method of creating just such a “personalized immune mouse.”  Read More

Image of a mouse with implanted tumors before and after receiving photoimmunotherapy (PIT)...

Besides surgery, chemotherapy and radiation are the foundation of modern day cancer treatment. Although effective, these therapies often have debilitating and damaging side effects. But scientists at the National Cancer Institute in Bethesda, Maryland have been experimenting with a new form of therapy using infrared light to kill cancer cells and shrink tumors without damaging healthy tissue.  Read More

An enhanced color image of fluorescence from single-walled carbon nanotubes (right) shows ...

Mice are frequently used as lab models when testing new drugs, and fluorescent dyes are sometimes injected into their bodies so that researchers can better see how those drugs are progressing through their systems. Unfortunately, the pictures obtained in this process start to become murky when imaging anything more than a few millimeters beneath the skin. Scientists from Stanford University have now devised a system that utilizes fluorescent carbon nanotubes to produce clear color images of organs that are located centimeters within a mouse's body.  Read More

The prototype BioExplorers system uses live sniffer mice to detect explosives (Photo: Rama...

Mice ... they may nibble our food, poop in our cupboards, and make us go "eek," but they may also someday keep us from getting blown up. Before they can do that, however, Israeli tech company BioExplorers has to get its mouse-based explosives detection system out of the prototype stage and into production. If it ever does see the light of day, then people at airports, arenas, and other high terrorism-risk areas may routinely be getting a sniff-down by containers of live rodents.  Read More

Satellite image using what is known as the Enhanced Vegetation Index (EVI) to show plant c...

Directly tracking disease-carrying mice from space would seem to be a tall order – and even without knowing the full capabilities of military satellites, I suspect the ability to do so is still a couple of years off yet. But researchers at the University of Utah have come up with an indirect way of tracking rodents by using satellite images to monitor surges in vegetation that boost mouse populations. Such a method could help forecast outbreaks of rodent-borne illnesses worldwide by allowing the creation of risk maps that show when and where outbreaks are likely to occur.  Read More

'Optical cuffs' been used to stimulate muscle movements in mice (Photo: Rama)

In a study that could eventually restore movement to humans’ paralyzed limbs, researchers at California’s Stanford University have used light to induce muscle contractions in mice. A gene derived from algae was inserted into the mice, encoding a light-sensitive protein which adhered to their nerve cell surfaces. Scientists then placed an “optical cuff” lined with tiny, inwards-facing LEDs around the mice’s sciatic nerves. By penetrating those nerves with brief, high-intensity bursts of blue light, they were able to produce muscle contractions similar to those that would occur naturally. The technology is called “optogenetics.”  Read More

Mice suffering retinitis pigmentosa have had their sight restored using gene therapy (Imag...

The classic nursery rhyme Three Blind Mice might need to be rewritten thanks to researchers from the Friedrich Miescher Institute (FMI) and the Institut de la Vision in Paris. Using gene therapy, the scientists have have restored sight in mice by repairing the function of cone photoreceptors made defective by a genetic eye condition.  Read More

The lightweight and ergonomic Aigo Glide Mouse

Recent developments in the war on repetitive strain injury have seen swiveling mice and applicable gel pads in an effort to make the everyday user experience a more comfortable one. Appearing at CES this year was another take on the ubiquitous peripheral, the Aigo Glide mouse. Designed to offer ease of use and minimal strain, the lightweight mouse features indentation for fingertips and side scrolling wheels, while the USB cord and connection even tuck away around and under the mouse for easy storage.  Read More

The Logitech Performance Mouse MX and Logitech Anywhere Mouse MX

Logitech has released a mouse that makes portable computing easier – one that operates on shiny surfaces. Utilising its Darkfield Laser Tracking, the company says its mouse can operate on virtually any surface – including clear glass (that’s at least 4mm thick) and other high-gloss surfaces found in today’s modern home and office. The technology is available in two models – the Logitech Performance Mouse MX (full-size) and the Logitech Anywhere Mouse MX (compact for notebooks).  Read More

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