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Medication

— Science

Organovo now selling tiny 3D-printed human livers

When a medication enters the bloodstream, it ends up being concentrated in the liver – after all, one of the organ's main functions is to cleanse the blood. This means that if a drug is going to have an adverse effect on any part of the body, chances are it will be the liver. It would seem to follow, therefore, that if a pharmaceutical company wanted to test the safety of its products, it would be nice to have some miniature human livers on which to experiment – which is just what San Diego-based biotech firm Organovo is about to start selling. Read More
— Health & Wellbeing

Memo Box, the smart pillbox that reminds you to take your medication

While forgetting to take the trash out might irritate your better half, forgetting to take your medication could have far more serious consequences. Memo Box is a device designed to replace the familiar plastic seven-day pill boxes that works in conjunction with a smartphone app to ensure you and your loved ones take prescribed medication at the right time, and in the right dose. Read More
— Medical

Organs-on-Chips emulate human organs, could replace animals in tests

The search for more efficient tests of pharmaceuticals without animal models is taking a stride forward, with a new technology being developed in the US called Organs-on-Chips. The new miniature platform and software, which mimic the mechanical and molecular characteristics of human organs, were developed by bioengineers from the Wyss Institute for Biologically Inspired Engineering at Harvard University. Read More
— Medical

Mini simulated cardiovascular system could speed testing of medications

When scientists want to find out how a new medication will affect the cardiovascular system, the traditional way of doing so is via animal or human trials. This takes time, can be potentially harmful to the test subjects, and doesn't always deliver conclusive results. Thanks to a device created at Coventry University in the UK, however, the testing process may soon be quicker, safer and more reliable. Read More
— Medical

Researchers engineer red blood cells to deliver therapeutic payloads

Although several studies are currently exploring the use of man-made nanoparticles for delivering medication to targeted areas of the body, care must be taken to ensure that those particles don't cause adverse reactions when introduced to the bloodstream. Scientists at the MIT-affiliated Whitehead Institute, however, are taking a different approach to the same basic concept. They've developed a method of attaching chemical payloads to red blood cells. Read More
— Medical

Prototype prints precise, patient-specific drug doses

It can be tricky to take exactly one fourths of a pill or the specific dose of prescribed medication, which is why researchers at Purdue University have come up with a way to print the proper dosage that a patient requires. Their prototype uses inkjet printing technology and a predictive mathematical model that calculates exactly how much medicine the patients needs and prints out the precise doses into tablets or films. Read More
— Health & Wellbeing

Vibrating capsule treats constipation by buzzing the intestine

According to Dr. Yishai Ron, a researcher at Tel-Aviv Sourasky Medical Center, nearly half of the people who take medication for chronic constipation are unsatisfied with the results. That dissatisfaction can stem from unwanted side effects, concerns over the long-term safety of the medication, or "the fact that it simply doesn’t work." That's why he and his colleagues have created an oral capsule that relieves constipation by vibrating its way along the intestinal tract. Read More
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