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Lifespan

Using a technique in which better cells in the body to be selected at the expense of more damaged ones, researchers at the University of Bern in Switzerland have managed to significantly increase the lifespan of the common fruit fly. Although most people would like to see flies living shorter, not longer lives, the development could have implications for increasing the lifespan of humans. Read More
With a typical lifespan of around six weeks, the common fruit fly is one animal that could benefit from a slowing of the aging process. And that's just what a team of biologists at UCLA have achieved by activating a gene called AMPK. Possibly of more interest to us higher life forms is the researchers' belief that the discovery could help delay aging and age-related diseases in humans. Read More
Researchers at the National Institutes of Health have found that suppressing the expression of a single gene in mice extends their average lifespan by about 20 percent – the equivalent of humans living an average of 95 years. While modification of the so-called mTOR gene may not lead to the fountain of youth, further study could open up a path to keeping us healthier and more alert in our old age. Read More
Instead of traipsing through Florida in search of the Fountain of Youth, Spanish explorer Juan Ponce de León might have been better off turning his search inwards. More specifically, he should have turned his attention to a region of the brain called the hypothalamus. At least that’s what research carried out on mice by scientists at New York’s Albert Einstein College of Medicine of Yeshiva University suggests. They found that the hypothalamus controls many aspects of aging, opening up the potential to slow down the aging process by altering signal pathways within that part of the brain. Read More
Technology has advanced markedly since the dawn of the silicon age, but our portable gadgets and gizmos are still largely held back by the limitations of their power source. Scientists at the Fraunhofer Institute for Material and Beam Technology IWS in Dresden report progress in this regard, with the development of a new longer-lasting lithium-sulfur battery that has the potential to outperform lithium-ion batteries, at a lower cost. Read More
Using the technique that created Dolly the sheep, researchers from the RIKEN Center for Developmental Biology in Kobe, Japan, have identified a way to produce healthy mouse clones that live a normal lifespan and can be sequentially cloned indefinitely. In an experiment that started in 2005, the team led by Dr. Teruhiko Wakayama has used a technique called somatic cell nuclear transfer (SNCT) to produce 581 clones of one original "donor" mouse through 25 consecutive rounds of cloning. Read More
The quest for longer and healthier life, if not immortality, has been part of the human experience since we evolved the ability to recognize the total annihilation of individual death. Our understanding of the biology of aging at the molecular level is advancing so rapidly that it appears inevitable that another decade or two of life will be enabled before long. A new step in what may be the right direction has just been published by researchers at the University of California, Berkeley. Read More

Another breakthrough in the ever accelerating quest to extend human lifespan has seen researchers identify key genes associated with ageing. By studying these "ageing" genes, which are switched on or off by external factors such a diet and lifestyle, it's hoped that the biological mechanisms of ageing can be better understood. Read More

A recent study suggests that, at least for worms, free radicals may not be the "bad guys" after all. It turns out that if you are a bacteria-eating worm of the species C. elegans, genetic modifications that raise your free radical levels don't have the negative effect expected, but instead serve to lengthen lifespan. Read More
For many scientists who know about such things, the question isn’t whether the first person to live forever has been born, but how old they are. The basis for this belief is that, if a person can survive the next 20 or 30 years, then breakthroughs in biotechnology will easily allow them to extend their lifespan – not to mention their quality of life – to 125 years. From that point, the advances will keep coming to allow the prolonging of life indefinitely. One of the first steps towards such a reality has just been announced by a group of researchers who have discovered the first compound that activates an enzyme called telomerase in the human body. Read More
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