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HIH researchers have found that suppressing the expression of a single gene in mice extend...

Researchers at the National Institutes of Health have found that suppressing the expression of a single gene in mice extends their average lifespan by about 20 percent – the equivalent of humans living an average of 95 years. While modification of the so-called mTOR gene may not lead to the fountain of youth, further study could open up a path to keeping us healthier and more alert in our old age.  Read More

The small almond-sized portion of the brain known as the hypothalamus could be the body's ...

Instead of traipsing through Florida in search of the Fountain of Youth, Spanish explorer Juan Ponce de León might have been better off turning his search inwards. More specifically, he should have turned his attention to a region of the brain called the hypothalamus. At least that’s what research carried out on mice by scientists at New York’s Albert Einstein College of Medicine of Yeshiva University suggests. They found that the hypothalamus controls many aspects of aging, opening up the potential to slow down the aging process by altering signal pathways within that part of the brain.  Read More

The new batteries were developed at the Fraunhofer Institute for Material and Beam Technol...

Technology has advanced markedly since the dawn of the silicon age, but our portable gadgets and gizmos are still largely held back by the limitations of their power source. Scientists at the Fraunhofer Institute for Material and Beam Technology IWS in Dresden report progress in this regard, with the development of a new longer-lasting lithium-sulfur battery that has the potential to outperform lithium-ion batteries, at a lower cost.  Read More

Mouse clones from the 24th and 25th generation of serial cloning (Photo: Riken)

Using the technique that created Dolly the sheep, researchers from the RIKEN Center for Developmental Biology in Kobe, Japan, have identified a way to produce healthy mouse clones that live a normal lifespan and can be sequentially cloned indefinitely. In an experiment that started in 2005, the team led by Dr. Teruhiko Wakayama has used a technique called somatic cell nuclear transfer (SNCT) to produce 581 clones of one original "donor" mouse through 25 consecutive rounds of cloning.  Read More

The SIRT3 protein molecule that appears to play a central role in regulating aging and lon...

The quest for longer and healthier life, if not immortality, has been part of the human experience since we evolved the ability to recognize the total annihilation of individual death. Our understanding of the biology of aging at the molecular level is advancing so rapidly that it appears inevitable that another decade or two of life will be enabled before long. A new step in what may be the right direction has just been published by researchers at the University of California, Berkeley.  Read More

A Kings College London study using groups of identical twins has identified genes that are...

Another breakthrough in the ever accelerating quest to extend human lifespan has seen researchers identify key genes associated with ageing. By studying these "ageing" genes, which are switched on or off by external factors such a diet and lifestyle, it's hoped that the biological mechanisms of ageing can be better understood.  Read More

A new study raises questions about one of the favored theories of aging involving increasi...

A recent study suggests that, at least for worms, free radicals may not be the "bad guys" after all. It turns out that if you are a bacteria-eating worm of the species C. elegans, genetic modifications that raise your free radical levels don't have the negative effect expected, but instead serve to lengthen lifespan.  Read More

An illustration of a telomerase molecule (Image: Sierra Sciences, LLC)

For many scientists who know about such things, the question isn’t whether the first person to live forever has been born, but how old they are. The basis for this belief is that, if a person can survive the next 20 or 30 years, then breakthroughs in biotechnology will easily allow them to extend their lifespan – not to mention their quality of life – to 125 years. From that point, the advances will keep coming to allow the prolonging of life indefinitely. One of the first steps towards such a reality has just been announced by a group of researchers who have discovered the first compound that activates an enzyme called telomerase in the human body.  Read More

It doesn't seem to matter how the diet is restricted - whether fats, proteins or carbohydr...

Researchers at Mount Sinai School of Medicine have unraveled a molecular puzzle to reveal why a lower-calorie diet slows the development of some age-related conditions such as Alzheimer’s disease, as well as the aging process itself. In their search for an answer they discovered that it doesn’t seem to matter how the diet is restricted – whether fats, proteins or carbohydrates are cut – to produce protective effects against aging and disease.  Read More

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