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Insulin

Aside from the inconvenience of injecting insulin multiple times a day, type 1 diabetics also face health risks if the dosage level isn’t accurate. A new approach developed by US researchers has the potential to overcome both of these problems. The method relies on a network of nanoscale particles that once injected into the body, can maintain normal blood sugar levels for more than a week by releasing insulin when blood-sugar levels rise. Read More
Researchers from the Universitat Autònoma de Barcelona (UAB) have claimed a first by successfully using a single session of gene therapy to cure dogs of type 1 diabetes. The work has shown that it is possible to cure the disease in large animals with a minimally-invasive procedure – potentially leading the way to further developments in studies for human treatment of the disease. Read More
Despite decades of study, scientists remained unsure as to how insulin binds to the insulin receptor on the surface of cells to allow them to take up sugar from the blood and transform it into energy. Now, a definitive answer has now been found with a team of scientists capturing the first three-dimensional images of insulin “docking” to its receptor. It is hoped that the new knowledge can be exploited to develop new and improved insulin medications to treat type 1 and type 2 diabetes. Read More
According to the World Health Organization, there are currently 347 million diabetics worldwide, with 90 percent of those people having type II diabetes specifically. It occurs when fat accumulates in places such as muscles, blood vessels and the heart, causing the cells in those areas to no longer be sufficiently responsive to insulin. This insulin resistance, in turn, causes blood glucose levels to rise to dangerous levels. Ultimately, it can result in things such as heart disease, strokes, blindness, kidney failure, and amputations. Fortunately, however, an international team of scientists has just announced a new way of treating the disease. Read More
New research carried out at São Paulo University’s School of Medicine in Brazil reveals that HDL concentrations in the blood influence the synthesis and absorption of cholesterol by the body, besides being linked to how insulin impacts on the metabolism of glucose. HDL, or high-density lipoprotein, is also commonly referred to as "good cholesterol." Read More
Researchers from Purdue University in Indiana are testing a compound found in red wine that has the ability to block the processes of fat cell development. The research into the compound known as piceatannol may lead towards finding a simple method to combat obesity. Read More
The World Diabetes Foundation estimated that some 285 million people, or around 6 percent of the world's adult population, were living with diabetes in 2010. For type 1 diabetics and up to 27 percent of type 2 diabetics, that means daily insulin injections, which can be uncomfortable and inconvenient. Since most people would rather pop a pill than get a shot, researchers have been trying to develop an oral form of insulin. However, this has proven difficult because insulin is a protein that is broken down in the stomach and gut. Now a team of researchers from Australia's Curtin University has found an insulin substitute to treat diabetes orally that they hope could help take the needle out of diabetes for many people. Read More
If a just-announced research project is successful, then maybe – just maybe – diabetics will finally be free of having to perform daily finger prick blood tests and insulin injections. Based on new findings regarding the body’s production of insulin, Mayo Clinic endocrinologists Yogish Kudva and Ananda Basu are in the process of developing an artificial pancreas, that would automatically deliver the hormone when needed. Read More
With the number of apps in Apple’s App Store standing at more than 250,000 it’s no surprise that there are a number of diabetes-related apps amongst them. Such apps require users to manually enter information such as glucose numbers, carbohydrate consumption, insulin dosages and activities to allow diabetics to better control the disease. A new plug-in attachment for the iPhone and iPod touch called the iBGStar takes things one step further by incorporating a blood glucose meter that allows users to view and analyze readings in ‘real time’. Read More
According to the American Diabetes Association around one in every 400 to 600 children and adolescents has type 1 diabetes – also known as IDDM, or juvenile diabetes. Currently there is no known way to prevent the disease which requires sufferers to administer insulin usually via injection or a pump. Using a nanotechnology-based "vaccine," researchers were able to successfully cure mice with type 1 diabetes and slow the onset of the disease in mice at risk for the disease. Read More
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