Harvard

Whether caused by intubation during surgery, laryngeal cancer, lesion removal, or simply overuse, vocal cord scarring can limit or even eliminate some peoples' ability to speak. This is because the scar tissue is stiff, and doesn't allow the vocal cords to vibrate adequately. Some doctors have tried to soften the tissue using materials from the fields of plastic surgery and dermatology, but the treatment doesn't work in all cases, and the effects are said not to last very long. Researchers from the Massachusetts Institute of Technology (MIT) and Harvard Medical School, however, are developing a new approach - an injectable gel that mimics vocal cord tissue.  Read More

While scientists have long had the ability to edit individual genes, it is a slow, expensive and hard to use process. Now researchers at Harvard and MIT have developed technologies, which they liken to the genetic equivalent of the find-and-replace function of a word processing program, that allow them to make large-scale edits to a cell’s genome. The researchers say such technology could be used to design cells that build proteins not found in nature, or engineer bacteria that are resistant to any type of viral infection.  Read More

Autonomous robotic devices are certainly capable of some impressive feats, but as is the case with people, sometimes large groups can accomplish what an individual or a small group can’t. Research projects such as BAE Systems’ MAST program recognize this potential, and are investigating ways in which entire swarms of small robots could work together. The problem is, given how much time and money goes into the creation of a typical autonomous robot, it’s difficult to find a swarm of them to experiment upon – researchers often have to use computer simulations, or do their tests with a small group of robots, then scale up the results. That’s where Harvard University’s Kilobot project comes into play. It incorporates tiny swarming robots that take just five minutes to build, and that are worth about US$14 each.  Read More

There's no doubt that residents of developing nations can benefit hugely from having mobile phones. This particularly applies to the field of medicine, as the phones allow people living in remote areas to contact health care practitioners, or to use health care apps. Given how unreliable the electrical grid can be in such countries, however, keeping those phones charged can be a challenge. That's why a team from the Harvard School of Engineering and Applied Sciences (SEAS) is working on a microbial fuel cell-based charger – a mobile phone charging system that gets its power from microbes in the soil.  Read More

A cross-discipline project that brings together biomedicine and nano-engineering has led to the development of a dime-sized microfluidic device that can rapidly detect cancer cells in a blood sample. The new device is based on a cancer cell-detector created four years ago by Mehmet Toner, professor of biomedical engineering at Harvard Medical School. In its latest incarnation, carbon nanotubes have been introduced into the design resulting in an eight-fold improvement in the collection of cells.  Read More

It’s certainly an established fact that electricity can cause fires, but today a group of Harvard scientists presented their research on the use of electricity for fighting fires. In a presentation at the 241st National Meeting & Exposition of the American Chemical Society, Dr. Ludovico Cademartiri told of how they used a unique device to shoot beams of electricity at an open flame over one foot tall. Almost immediately, he said, the flame was extinguished. On a larger scale, such a system would minimize the amount of water that needed to be sprayed into burning buildings, both saving water and limiting water damage to those buildings.  Read More

Men are from Mars and women are from Venus. That's one theory ... another is that all life on Earth descended from organisms that originated on the Red Planet before hitching an interplanetary journey aboard meteorites to Earth. In an effort to provide a definitive answer, researchers at MIT and Harvard are developing an instrument to compare the genetic makeup of Martian microbes with that of terrestrial life. If they find correlations between the two it could prove that we are all descended from Martians, which would make us invaders from Mars.  Read More

For decades, chipmakers strove to develop the fastest and most powerful chips possible and damn the amount of electricity needed to power them, but these days raw grunt isn't the only consideration. As more and more devices go mobile and these devices become more and more powerful, chipmakers must also take the energy efficiency into account. Harvard graduate student Wonyoung Kim has developed and demonstrated an on-chip, multi-core voltage regulator (MCVR) that he says could allow the creation of "smarter" smartphones, slimmer laptops and more energy efficient data centers by more closely matching the power supply to the demand of the chip.  Read More

Scientists and MDs have a wide range of technologies available for the imaging of live tissue, but each of these comes with its own limitations - be it poor contrast, low resolution, long response times or the viewing process damaging the tissue being observed. A team of Harvard researchers has developed a new type of optical biomedical imaging that promises to overcome these obstacles and is so fast and high-resolution that it can capture live video of cells and molecules.  Read More