Genetic engineering
Landmark decision? US Supreme Court rules human genes cannot be patented
In what is being ballyhooed as a landmark decision likely to set the course of DNA-based diagnostic and therapeutic medicine for the next several decades, the US Supreme Court unanimously decided on June 13 that human genes are not patentable. Rather than objects invented or discovered, human genes are henceforth to be treated as "naturally occurring phenomena," and hence fail the patentability test under 35 USC 101. As is usual in patent cases, however, the ruling contains delicate shades of meaning. Read More
It has long been believed that detecting carbon dioxide was one of the ways that mosquitoes target their human prey. But the fact that mosquitoes tend to favor certain people over others indicates that some other odor also plays a part in the attraction. Researchers at the Howard Hughes Medical Institute (HHMI) have genetically engineered mosquitoes to alter their sense of smell, which could provide the understanding required to block the pesky pests' attraction to humans. Read More
Atherosclerosis, more commonly known as hardening of the arteries, can have very serious consequences such as heart attacks and strokes. While there are medications that remove some of the offending plaque from the inside of the affected arteries, not everyone wants to take drugs unless absolutely necessary. Lifestyle improvements can certainly help, but soon two other options may be available – probiotics and genetically-engineered tomatoes. Read More
For the first time ever, a computer model of a complete living organism has been created. True, it’s a single-celled organism – in fact, it’s the world’s smallest free-living bacterium, Mycoplasma genitalium. Still, all of its systems and the relationships between them have been replicated in silico, allowing scientists to conduct research that might otherwise have proved impossible. It also paves the way for computer modeling of more complex organisms, such as humans. Read More
Last year, Prof. Anthony James announced that he and his colleagues had genetically altered Aedes aegypti mosquitoes in a fashion that could drastically reduce their populations. In a nutshell, the altered genes cause the female mosquitoes to be born without wings – this makes it rather difficult for them to go foraging for blood, and turns them into easy prey for almost any predator. The non-biting males are born with wings, and subsequently go off and mate with unmodified females, passing the modified genes along to their offspring. Now, James has done some more genetic engineering, to create mosquitoes that can’t spread malaria. Read More
He can't fly just yet, but a team of scientists have made a big step towards creating a real-life Mighty Mouse. Researchers at the Salk Institute for Biological Studies, along with two Swiss institutions, Ecole Polytechnique Federale de Lausanne (EPFL) and the University of Lausanne, created a batch of super-strong mice and worms by tweaking a gene that normally inhibits muscle growth. Read More
Caloric restriction has been shown to slow the signs of aging and delay the development of age-related diseases in a wide range of animals. However, scientists have been unable to explain just why limiting daily food intake has such a beneficial effect on health and the biological mechanisms that underlie the phenomenon. Researchers in Sweden recently claimed to have unlocked a piece of the puzzle by identifying one of the enzymes that appears to play a major role in the process and now another group in the U.S. has provided another clue by tweaking a gene in fruit flies and extending their lifespan by as much as 50 percent. Read More
There are several techniques used by researchers and physicians to image the internal organs of people and animals, but each of these techniques have their shortcomings. X-rays and computed tomography (CT) scanning, for instance, involve exposing the subject to radiation. Magnetic resonance imaging (MRI) is safer, although subjects must sometimes ingest a contrasting agent in order to obtain more distinct images. The use of injected colored fluorescent proteins is another approach, but has been limited by the fact that hemoglobin in the subject’s blood absorbs much of the wavelength of the light used for imaging. Now, however, scientists from New York’s Albert Einstein College of Medicine of Yeshiva University have engineered a new fluorescent protein that sidesteps this limitation. Read More
While laser beam-shooting plants or animals might seem like something straight out of Star Trek, two researchers from the Wellman Center for Photomedicine at Massachusetts General Hospital recently wondered whether such organisms could theoretically exist. In order to satisfy their curiosity, Dr. Malte Gather and Dr. Seok Hyun Yun successfully created a laser that uses a living cell as its light source. The device, which utilizes a protein found in jellyfish, could have applications in the fields of biomedicine and optical computing. Read More
According to a recent report on Sky News, Chinese scientists have created a herd of 300 transgenic dairy cattle, all of which have been genetically modified to produce human breast milk. While the milk is still undergoing government testing, the researchers reportedly hope to be selling it in supermarkets within three years. Read More