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Drugs

Endothelial cells grown from stem cells in the blood, stained with fluorescent markers (Ph...

Scientists have developed a blood test using human stem cells that predicts whether new drugs will cause severe side effects. The test, which only requires blood from a single donor, could help prevent catastrophic inflammatory reactions known as a cytokine storm in people participating in drug trials.  Read More

A new technique involving magnetic nanoparticles allows therapeutic molecules to cross the...

The blood-brain barrier is a highly selective semipermeable barrier running inside almost all vessels in the brain that lets through water, some gases and a few other select molecules, while preventing potentially toxic elements in the blood from entering the brain. Researchers from the University of Montreal, Polytechnique Montréal, and CHU Sainte-Justine say that currently 98 percent of therapeutic molecules are also blocked by the barrier, but they have developed a technique using magnetic nanoparticles that opens the door for such molecules, thereby also opening the door to new treatments for brain diseases.  Read More

Eve is capable of making and amending hypotheses based on testing (Photo: University of Ma...

Modern pharmaceuticals are a wonder of our age, but they also take years to develop at incredible cost. To shorten development time and increase economy, scientists at the Universities of Cambridge and Manchester have built Eve, an artificially-intelligent "robot scientist" that is not only faster and cheaper than its human counterparts, but has already identified a compound that could be used to fight malaria.  Read More

Scientists have discovered a compound that neither Methicillin-resistant Staphylococcus au...

Over the past quarter century, many pharmaceutical companies have largely turned their backs on the quest to develop new antibiotics, blaming difficulties surrounding the clinical trials process and turning their attention to the more profitable development of so-called "lifestyle drugs." One company bucking the trend is NovoBiotic Pharmaceuticals, which has announced the discovery of a new class of antibiotic that holds promise for treating drug-resistant superbugs.  Read More

3D printing models of tumors and their surrounding organs could help specialists to delive...

Administering the correct dosages to fight cancerous tumors can be a difficult balancing act. Too much of the radioactive drugs can cause harm to healthy tissue, but not enough will see the cancer cells survive and continue to spread. But a new technique developed at The Institute of Cancer Research in London may afford doctors an unprecedented level of accuracy in performing radiotherapy, using 3D-printed replicas of a patient’s organs and tumors to better determine how much radiation a tumor has received.  Read More

Encapsulated toxin-producing stem cells (in blue) help kill brain tumor cells in the tumor...

When it comes to new tumor-fighting treatments, it’s often as much about location, location, location as it is the actual drug interaction. Cytoxin-producing stem cells produced by scientists at Harvard University lodge at the site of brain tumor removal to continually attack remaining tumor cells. As an alternative to drug treatments that can be invasive or ineffective, the researchers saw promising results against glioblastomas, which hold the dubious distinction of being the most common and most fatal brain cancer.  Read More

An existing overdose-treatment drug is now being tested in nasal spray form (Photo: Shutte...

Heroin overdoses are typically treated using injections of a medication that resuscitates the victim. That's fine if paramedics are doing it, but not everyone feels comfortable giving someone else a needle. That's why scientists at the Norwegian University of Science and Technology (NTNU) are developing a nasal spray that does the job.  Read More

Diagram of the capsule releasing its pharmaceutical payload into the intestinal lining (Im...

MIT, working together with the Massachusetts General Hospital (MGH), has pioneered a method of drug distribution with the potential to dispense with traditional subcutaneous injections. The system uses a small capsule coated with microneedles in order to administer medicines directly into the lining of the intestine.  Read More

Fusing 3D-printed beads with antibacterial or chemotherapeutic compounds provides the pote...

A great strength of 3D-printing in the field of medicine is the ability to provide low-cost, personalized implants molded to a patient's anatomy. Researchers from Louisiana Tech University have now taken the technology one step further, loading these custom implants with cancer-fighting and antiobiotic compounds as a means of better targeted drug delivery.  Read More

A dissolving tampon could offer fast-acting HIV protection (Image: University of Washingto...

Researchers at the University of Washington (UW) have developed a material that could offer women a new means of protection against HIV. Demonstrated in the form of a tampon, the material is capable of carrying substantial loads of medicine, dissolving and releasing the drugs once its comes into contact with moisture.  Read More

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