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Disease

The above image of a cancer cell by Jane Stout of Indiana University won the microscopy ca...

We report on the latest developments in biological research all the time here at Gizmag, but it's easy to forget just how beautiful biology can appear when observed at the cellular level. On this note, GE Healthcare’s Life Sciences Cell Imaging Competition has announced its winners for 2012, giving us the opportunity to appreciate the images which will soon light up New York’s Times Square.  Read More

Led by Fàtima Bosch (fifth from left), a University of Barcelona research team has cured d...

Researchers from the Universitat Autònoma de Barcelona (UAB) have claimed a first by successfully using a single session of gene therapy to cure dogs of type 1 diabetes. The work has shown that it is possible to cure the disease in large animals with a minimally-invasive procedure – potentially leading the way to further developments in studies for human treatment of the disease.  Read More

Scientists have used microneedle arrays to store a live vaccine at room temperature, and a...

While it’s vitally important to bring vaccines for diseases such as tuberculosis to developing nations, getting them there is only part of the challenge. Because these countries often have unreliable infrastructures, it’s entirely possible that the vaccines can’t consistently be kept as cold as is required. As a result, they could be rendered ineffective. Now, however, scientists from King’s College London have succeeded in containing a dried live vaccine in a microneedle array, that doesn’t need to be refrigerated.  Read More

David’s myotis, a tiny insectivorous bat native to China, was one of two bat species selec...

Scientists believe the genes of virus-resistant and long-living wild bats might hold clues to treating cancer and infectious diseases in humans. The theory is that when bats started flying millions of years ago, something changed in their DNA that provides resistance to viruses and helps give them a relatively long life. The researchers hope a better understanding of bat evolution could lead to new treatments for disease and aging in humans.  Read More

A modified form of a protein found in the HIV virus (pictured) has been shown to keep that...

Although there is still much work to do before human trials can even be considered, a scientist from Australia’s Queensland Institute of Medical Research has created a protein that reportedly keeps HIV from progressing into AIDS. Perhaps ironically, that protein is a mutated form of one found in the HIV virus itself.  Read More

Microbiologist Emma Allen-Vercoe and her lab team, whipping up a batch of RePOOPulate

If the clostridium difficile bacterium becomes over-abundant in a person’s colon, the results can include gastrointestinal problems such as severe diarrhea. Ordinarily, c. difficile populations are kept in check by the usually-present beneficial gut bacteria. If those “good” bacteria are killed off as a side effect of taking antibiotics, however, the nasties can take over. The treatment? Well ... it often involves having another person’s stool implanted in your gut via enema. Yikes. Fortunately, a less icky treatment is in the works, that involves the use of a “synthetic poop” known as RePOOPulate.  Read More

A 3D image of a rotavirus, constructed from data gathered using the new technique

Traditionally, in order to view tiny biological structures such as viruses, they must first be removed from their natural habitats and frozen. While this certainly keeps them still for the microscope, it greatly limits what we can learn about them – it’s comparable to an ichthyologist only being able to study dead fish in a lab, instead of observing live ones in the ocean. Now, however, researchers at the Virginia Tech Carilion Research Institute have devised a technique for observing live viruses in a liquid environment. It could have huge implications for the development of treatments for viral infections.  Read More

Anopheles mosquito after taking a snack (Photo: US Center for Disease Control and Preventi...

A small company in the U.K. is developing an affordable, hand-held device that will not only diagnose malaria in the field, but will also read DNA markers that suggest which antimalarial drugs will be most effective for treatment. If fielded, such a device could help alleviate the 200+ million cases of malaria per year, as well as prevent some of the nearly one million deaths associated with malarial illness.  Read More

'If this could be used as a treatment one day, it is conceivable that patients would only ...

Scientists at The Rockefeller University have found that harnessing proteins from the human immune system can suppress the HIV virus in mice. Potentially, this could lead to a therapeutic approach to treating the virus that does not require a daily application of drugs.  Read More

A team of scientists has devised a new approach to treating type II diabetes (Photo: Shutt...

According to the World Health Organization, there are currently 347 million diabetics worldwide, with 90 percent of those people having type II diabetes specifically. It occurs when fat accumulates in places such as muscles, blood vessels and the heart, causing the cells in those areas to no longer be sufficiently responsive to insulin. This insulin resistance, in turn, causes blood glucose levels to rise to dangerous levels. Ultimately, it can result in things such as heart disease, strokes, blindness, kidney failure, and amputations. Fortunately, however, an international team of scientists has just announced a new way of treating the disease.  Read More

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