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Chemotherapy

Gold nanostars like these are able to deliver drugs directly into the nucleus of cancer ce...

While effective at killing cancer cells, chemotherapy is currently a shotgun approach that can also harm healthy cells and cause serious side effects in patients. The ability to deliver drugs directly into cancer cells would provide a more targeted approach to more effectively treat the disease with lower doses of drugs and less side effects. Researchers at Northwestern University are claiming to be the first to develop gold nanostars that provide a much more precise approach by delivering a drug directly to a cancer cell’s nucleus.  Read More

The NovoTTF treatment involves placing pads onto the patient's skin that creates a low int...

The FDA (US Food and Drug Administration) has approved a new treatment for patients as an alternative to chemotherapy. The promising new non-invasive treatment by Novocure uses "Tumor Treating Fields" (NovoTTF) to treat cancerous growths and is now available for adult patients with recurring brain tumors (recurrent glioblastoma or GBM). The treatment delivers electric fields to a patient utilizing a portable, wearable device that permits the patient to maintain normal daily activities without down time.  Read More

Image of a mouse with implanted tumors before and after receiving photoimmunotherapy (PIT)...

Besides surgery, chemotherapy and radiation are the foundation of modern day cancer treatment. Although effective, these therapies often have debilitating and damaging side effects. But scientists at the National Cancer Institute in Bethesda, Maryland have been experimenting with a new form of therapy using infrared light to kill cancer cells and shrink tumors without damaging healthy tissue.  Read More

We’ve previously looked at the development of cancer treatments that deliver drugs directly into cancer cells before releasing their chemotherapeutic payload to reduce the damage done to healthy cells. But a new protein “switch” approach developed by researchers at Johns Hopkins University changes the game again by instructing cancer cells to produce their own cancer medication, causing the cancer cells to self-destruct while sparing healthy tissue.  Read More

The miniature device (right) that fits inside a tube (left) and can then be inserted into ...

Some cancers, such as pancreatic and cervical cancers, are notoriously hypoxic, which means they contain low oxygen levels. Because radiation therapy needs oxygen to be effective, hypoxic areas of a tumor can be difficult to kill. To combat this, researchers at Purdue University have developed and tested a miniature electronic device that is designed to be implanted into solid tumors to generate oxygen and boost the effectiveness of radiation and chemotherapy treatments.  Read More

Researchers liken their breakthrough to a cluster bomb for cancer (Image: KGH and Shutters...

Although chemotherapy is an effective cancer treatment, it’s shotgun approach also damages healthy cells bringing debilitating side effects such as nausea, liver toxicity and a battered immune system. Now a new way to deliver this life-saving therapy to cancer patients by getting straight to the source of the disease has been developed. The researchers responsible for the breakthrough delivery vehicle liken it to a cluster bomb for cancer because of its ability to deliver the drugs directly into cancer cells before releasing its chemotherapeutic payload.  Read More

After 24 hours, the cancer cells have taken up chimeric polypeptide-chemo combination (sho...

Blood vessels that supply tumors are more porous than normal vessels, makes nanoscale drug delivery systems a particularly attractive prospect. If properly engineered, nanoparticles can in fact get inside a tumor, targeting it precisely and allowing much higher drug dosages as they reduce side effects to a minimum. Two recent studies featured in the latest issue of the journal Nature Materials specifically address these issues and give us promising leads in the fight against cancer.  Read More

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In this week's Gizcast, Geoffrey Baird speaks with audiologist Anthea Arkcoll about a new type of hearing aid that bypasses the ear altogether and uses bone conduction technology to send a direct signal to the auditory nerve. Then Loz Blain wraps up with some of the most interesting electric and green car concepts the Giz team are drooling over in Frankfurt, and a quick look at a medical device that could give doctors a new way to fight stubborn cancer tumours.  Read More

The IsoFlow Isolation Catheter in action.

A Silicon Valley entrepreneur, after watching helplessly through his sister's painful and terminal battle with cancer, has spent the last 9 years working on a system that lets doctors cut off blood flow to tumors, isolating them from the rest of the body and allowing the injection of a targeted dose of high intensity chemotherapy. Since the chemo drugs aren't let loose around the rest of the body, the usual devastating side-effects aren't an issue - and the drug dosage at the tumor site can be safely administered at a much higher concentration than usual. The IsoFlow Isolation Catheter has just received FDA marketing approval in the USA.  Read More

Nanoparticles laden with chemotherapeutic drugs will target cancerous cells (Credit: Jacqu...

Researchers at the University of Central Florida have engineered nanoparticles that can target and destroy cancerous cells, delivering a chemotherapeutic drug directly to a tumor without harming healthy cells. This technology could not only mean the end of toxic, whole-body chemotherapy, but also provide a diagnostic role in the early detection of cancer.  Read More

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