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Cells

The benefits of using sound to separate cells over conventional more aggressive methods me...

Researchers from MIT, Carnegie Mellon University and Pennsylvania State University have developed a novel technique of separating cells with the use of a gentle sound wave. The technique could potentially be used to screen a patient's blood, allowing medical practitioners to isolate rare tumor cells synonymous with diseases such as cancer.  Read More

A new multi-purpose nanoparticle has shown to possess both diagnostic and drug-delivering ...

Nanoparticles hold great potential as a way of both detecting cancer cells and delivering the drugs to treat them. One hurdle that has proven difficult to overcome is incorporating these properties into one multi-purpose device, as nanoparticles are generally engineered with either goal in mind. In what appears a promising development, researchers at the University of California Davis (UC Davis) Cancer Center have created a multi-tasking nanoparticle shown to be effective both in the diagnosis of a tumor and attacking its cells – a flexibility that could lead to new treatment options for cancer patients.  Read More

MIT's porous tissue scaffold, as imaged by an electron microscope (Image: MIT)

A team of chemical engineers from MIT has developed a new method of stimulating bone growth, by utilizing the same chemical processes that occur naturally in the human body following an injury such as a broken or fractured bone. The technique involves the insertion of a porous scaffold coated with growth factors that prompt the body's own cells to naturally mend the damaged or deformed bone.  Read More

A team of international researchers has developed a new synthetic molecule that triggers s...

A team of international researchers has developed a molecule capable of triggering cancer cell death by carrying chloride into cancer cell membranes. The molecule flushes the cells with salt and causes them to self-destruct, potentially paving the way for new types of anti-cancer drugs.  Read More

A lab mouse body, one week after after the start of the PARS process – the arrow in the mi...

Ordinarily, when scientists want to see specific cells within a piece of biological tissue, they first have to remove that tissue from the body, slice it very thin, then examine those two-dimensional slices using a microscope. Imagine, though, if the tissue could be made transparent – seeing tagged cells within it would be sort of like looking at three-dimensional bubbles inside an ice cube. Well, that's just what a team at Caltech have done using a technique known as PARS, or perfusion-assisted agent release in situ.  Read More

Researchers have discovered a way to lower the defenses of antibiotic-resistant bacteria, ...

The discovery of antibiotics is one of the most important breakthroughs of the 20th century. But their effectiveness and low cost has led to their overuse, resulting in the worrying rise of antibiotic-resistant bacteria, or so-called superbugs. Researchers at the University of East Anglia (UAE) in England have now uncovered an Achille's heel in the bacterial cell defenses that could mean that bacteria wouldn't develop drug-resistance in the first place.  Read More

Electron micrograph of a flagellated Listeria monocytogenes bacterium, an infectious agent...

It is estimated that every year in America there are around 76 million food-borne illnesses that result in 325,000 hospitalizations and over 5,000 deaths. One of the main causes is the disease "Listeria", which has the highest hospitalization (92 per cent) and death (18 per cent) rate among all food-borne pathogen infections. Now researchers at the University of Southampton say that they are trialling a device designed to detect these bacteria directly on food preparation services, and without the need to send samples away for laboratory testing.  Read More

Bromine joins the other elements marked on this periodic table, as those critical for anim...

Joining the ranks of carbon, selenium, sulfur and 24 others as an essential element for animal life is element 35 – bromine – long considered inessential to life and moreso, shunned as a toxic disease-causing agent. However, researchers have identified the role bromine holds in animal development, even demonstrating death in fruit flies without access to this element named for its identifying stench.  Read More

A link has been discovered between a molecular scaffold and degenerative diseases such as ...

Researchers from King's College London (KCL) claim to have uncovered a link between a molecular scaffold, that allows for interaction between key components of a cell, and the debilitating effects of neurodegenerative diseases. It is possible in the long term that this line of research will yield a new target for tailored treatment in the fight against devastating afflictions such as dementia and motor neuron disease.  Read More

MIT's new nanoparticle carries three cancer-fighting drug molecules — doxorubicin is red, ...

Delivering drugs that can knock out tumor cells within the body, without causing adverse side effects, is a tricky busines. It's why scientists have taken to engineering new and creative types of nanoparticles that do the job. Increasing a nanoparticle's ability to carry more drugs expands treatment options, but creating nanoparticles capable of delivering more than one or two drugs has proven difficult – until now. Scientists at MIT report creating a revolutionary building block technique that's enabled them to load a nanoparticle with three drugs. The approach, they say, could be expanded to allow a nanoparticle to carry hundreds more.  Read More

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