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Cancer

HEALTH AND WELLBEING

Nanosized drug delivery systems take a leap forward

By Dario Borghino

19:03 November 3, 2009 PST

After 24 hours, the cancer cells have taken up chimeric polypeptide-chemo combination (sho...

Blood vessels that supply tumors are more porous than normal vessels, makes nanoscale drug delivery systems a particularly attractive prospect. If properly engineered, nanoparticles can in fact get inside a tumor, targeting it precisely and allowing much higher drug dosages as they reduce side effects to a minimum. Two recent studies featured in the latest issue of the journal Nature Materials specifically address these issues and give us promising leads in the fight against cancer. Read More

HEALTH AND WELLBEING

Magnetic nanotags detect cancer much earlier than current methods

By Jeff Salton

23:37 October 19, 2009 PDT

Stanford Professor Shan Wang and graduate student Richard Gaster, left, have developed an ...

Extremely sensitive nanosensor chips are being developed by Stanford University researchers in an attempt to detect the early signs of cancer, called biomarkers, in humans. The researchers say their sensor is around 1,000 times more sensitive than current technology and is accurate regardless of which bodily fluid is being analyzed. It can also detect biomarker proteins over a range of concentrations three times broader than any existing method. It is forecast that earlier detection of cancer biomarkers will lead to improved survival rates among cancer sufferers. Read More

HEALTH AND WELLBEING

3D cryo-imager can identify a single cancer cell

By Mick Webb

10:22 October 1, 2009 PDT

Image of cancer cells in the adrenal gland of a mouse
 (Image: Case Western Reserve Univer...

Recent developments in the fight against cancer have promised better ways to both identify and treat the disease. Adding to the ever growing list of advancements is Dave Wilson, a Professor of biomedical engineering at Case Western Reserve University in Cleveland. Frustrated by blurry low resolution optical images of diseased tissues, he has developed a cryo-imaging system which can identify and pinpoint the exact location and number of cancer cells in a particular area while displaying the findings as a detailed three dimensional color cyber model. Read More

HEALTH AND WELLBEING

A microchip that detects the type and severity of cancer in just half an hour

By Darren Quick

21:13 September 29, 2009 PDT

Lead researchers Shana Kelley and Ted Sargent with the cancer detecting microchips

Because the signature biomarkers that indicate the presence of cancer at the cellular level are generally present only at low levels in biological samples, detecting them is a procedure that usually takes days and involves a room filled with computers. Now researchers have used nanomaterials to develop a microchip small enough to fit in a device the size of a mobile phone, and sensitive enough to do the job in 30 minutes. Read More

HEALTH AND WELLBEING

Sugar-coating nanoparticles to tempt cancer cells brings dual benefits

By Darren Quick

23:58 September 23, 2009 PDT

An iron-centered nanoparticle (left) has a coating of the sugar dextran, whose tendrils pr...

Researchers believe nanoparticles hold the promise of battling cancer without the damaging side effects of chemotherapy or radiation treatment. They have discovered that coating minuscule balls of iron oxide with sugar molecules not only makes them particularly attractive to resource-hungry cancer cells, it also makes them more effective by allowing them to get close to each other, but not too close to render treatment ineffective. Read More

PODCASTS

Gizcast #11: bone conduction hearing implants, targeted chemotherapy and the electric car stampede that's storming Frankfurt

By Loz Blain

08:11 September 17, 2009 PDT

Subscribe to the Gizcast through iTunes.

In this week's Gizcast, Geoffrey Baird speaks with audiologist Anthea Arkcoll about a new type of hearing aid that bypasses the ear altogether and uses bone conduction technology to send a direct signal to the auditory nerve. Then Loz Blain wraps up with some of the most interesting electric and green car concepts the Giz team are drooling over in Frankfurt, and a quick look at a medical device that could give doctors a new way to fight stubborn cancer tumours. Read More

HEALTH AND WELLBEING

Targeted chemotherapy - fighting cancer without the side effects

By Loz Blain

02:28 September 14, 2009 PDT

The IsoFlow Isolation Catheter in action.

A Silicon Valley entrepreneur, after watching helplessly through his sister's painful and terminal battle with cancer, has spent the last 9 years working on a system that lets doctors cut off blood flow to tumors, isolating them from the rest of the body and allowing the injection of a targeted dose of high intensity chemotherapy. Since the chemo drugs aren't let loose around the rest of the body, the usual devastating side-effects aren't an issue - and the drug dosage at the tumor site can be safely administered at a much higher concentration than usual. The IsoFlow Isolation Catheter has just received FDA marketing approval in the USA. Read More

HEALTH AND WELLBEING

Gold nanoparticles used in early detection of lung cancer

By Jeff Salton

21:44 September 2, 2009 PDT

Gold particles are being used in a new breath-testing device to detect lung cancer in pati...

Gold nanoparticles are being used by researchers in Israel in a new type of breath test to detect lung cancer in patients. Breath particulate analysis isn’t new but the scientists say this is the first time a technique has been used without the need to pre-treat the exhaled breath, delivering a quicker and less expensive diagnosis. Early detection can result in faster treatment and hopefully save lives. Around 25 percent of all cancer-related deaths are lung cancer sufferers, with estimates put at around 1.3 million people dying from the disease each year. Read More

RESEARCH WATCH

Painting brain tumors with nanoparticles may help defeat cancer

By Michael Mulcahy

22:52 August 12, 2009 PDT

A mouse brain tumor imaged using nanoparticles (left) compared to conventional techniques ...

Nanotechnology is preoccupying science to the point where it's starting to seem unremarkable. But a group of researchers from the University of Washington has released findings that could profoundly improve the chances of surviving brain cancer. The team has developed a fluorescent nanoparticle that is capable of penetrating – for the first time – the blood-brain barrier without damaging it. The fluoro nanoparticle targets tumors using a derivative of scorpion venom and enables precise imaging of the size and location of cancerous growths. When the particles meet the tumor, they light up like Christmas. Read More

RESEARCH WATCH

Treating tumors by blasting nanotubes with a laser

By Darren Quick

22:33 August 11, 2009 PDT

SEM micrograph of Multi Walled Carbon Nanotube bundles at about 7220x magnification (Photo...

Current heat treatments for human tumors, such as radiofrequency, have shown promising results over the last couple of decades, even though they apply only a single-point of heat to the tumor. However, a new technique could prove much more effective by using nanotubes to apply heat throughout the tumor. Scientists found that by injecting the man-made, microscopic carbon tubes into tumors and heating them with a quick, 30-second zap of a laser, they were able to effectively kill kidney tumors in nearly 80 percent of mice. Read More

RESEARCH WATCH

Possible cure for radiation sickness discovered?

By Darren Quick

23:38 July 21, 2009 PDT

No need to worry, it's just a nuclear blast

According to a report in the Israeli newspaper, Yediot Ahronoth, US and Israeli researchers have developed a drug that offers protection from the damaging effects of radiation sickness. The medication could not only provide effective protection in the event of a nuclear or “dirty bomb” attack, but it could also enable cancer patients to be treated with more powerful doses of radiation. Read More

HEALTH AND WELLBEING

Biodegradeable nanoparticles promise end to toxic chemotherapy treatments

By Michael Mulcahy

03:23 June 19, 2009 PDT

Nanoparticles laden with chemotherapeutic drugs will target cancerous cells (Credit: Jacqu...

Researchers at the University of Central Florida have engineered nanoparticles that can target and destroy cancerous cells, delivering a chemotherapeutic drug directly to a tumor without harming healthy cells. This technology could not only mean the end of toxic, whole-body chemotherapy, but also provide a diagnostic role in the early detection of cancer. Read More

HEALTH AND WELLBEING

Nanodiamonds promise next-Generation Cancer Treatments

By David Greig

03:55 May 22, 2009 PDT

Assist. Prof. Dean Ho and Prof. Horacio Espinosa

Nanomaterials less than 100-thousand-millionths of a meter in size have the potential to radically change current drug delivery techniques with early trials showing the ability of nanomaterials to moderate the release of highly toxic chemotherapy drugs with reduced side effects and improved targeting. Using nanodiamonds, researchers at the McCormick School of Engineering and Applied Science have demonstrated a new tool designed to precisely deliver tiny doses of drug-carrying to individual cells - the Nanofountain Probe. Read More

HEALTH AND WELLBEING

Cancer monitoring implant could put lab inside the patient

By Darren Quick

23:02 May 18, 2009 PDT

The 5-mm implant, right, can monitor how a tumour responds to treatment
 Photo credit: Mic...

A new implantable device that monitors a tumor for weeks, or months, could offer a simpler, less intrusive alternative to taking biopsies, which are traditionally used to diagnose the presence of cancer – and one that potentially offers a greater chance of successful treatment. Read More

HEALTH AND WELLBEING

Gold nanospheres search out and ‘cook’ cancer cells

By Karen Sprey

21:48 March 23, 2009 PDT

Partial view of a gold nanosphere magnified by a factor of one billion. The darker ring sh...

March 24, 2009 A minimally invasive therapy that could help fight cancer may be on its way with the development of the first hollow gold nanospheres that actively search for and burn tumors. Researchers believe the new technique could prove particularly effective against malignant Melanoma, a deadly form of skin cancer responsible for around 48,000 deaths worldwide each year... and numbers are growing. Read More

 
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