Detecting cancer when it's still in the early stages of development is a difficult task, but an extremely important one, with the chances of effective treatment being much higher the quicker it's caught. Now, a team of researchers from the National Institute of Health (NIH) has identified a signature of tumor DNA that occurs, and is detectable, in five different cancers – a discovery that could lead to a simple early detection blood test.
A team of researchers from the Institute of Bioengineering and Nanotechnology at the Agency for Science, Technology and Research (A*STAR) has worked to develop an efficient technology that uses DNA to detect and treat infectious diseases. Improving upon an existing method, the research makes use of single-stranded DNA molecules called aptamers, and it could be used to treat cancer.
It could be possible to look for molecular alternations in breast tissue to identify whether a patient is at risk of developing breast cancer, a new study has found. Scientists at University College London (UCL) looked at changes in patient DNA, finding clear evidence that epigenetic alterations play a part in the occurrence of the disease.
Treating late-stage liver cancer can be extremely difficult, with drugs that prove effective in healthy organs causing high levels of toxicity when introduced to cirrhotic livers. A newly-developed nanoparticle delivery system could improve the situation, with early tests showing it to be effective as a non-toxic treatment in experiments with laboratory mice.
Our body has controls in place to regulate how cells grow and divide, which is a particularly useful mechanism in preventing the spread of disease. But when it comes to acute myeloid leukaemia (AML), an aggressive form of blood cancer, these controls are neutralized, giving the cancer cells free rein to multiply and grow uncontrollably. Australian researchers have now discovered a protein that drives this process, and have shown that by blocking its activity they might be able to stop the deadly form of cancer in its tracks.
The chemotherapy drug paclitaxel is commonly used to treat breast, lung and pancreatic cancers, slowing their growth by preventing cancerous cells from replicating. But once administered the drug is attacked by the body's defenses, necessitating larger doses that result in complications such as joint pain, diarrhea and an impaired ability to fend off other infections. Researchers have now discovered a way to sneak the drug through to the tumor with its entire payload intact, a technique that could make for more effective cancer treatments with fewer side effects.
A team of University of Glasgow researchers has worked to improve the imaging provided by swallowable cameras used to detect cancers in the throat and gut. The new video pills are able to emit fluorescent light, allowing the researchers to better analyze the returned imagery.
Back in January, a Johns Hopkins University study was released claiming that two-thirds of adult cancers are down to random mutations, or more simply put – bad luck. Now, a team of researchers from Stony Brook University is refuting that claim, providing an alternative analysis that counters the argument, stating instead that external factors actually play a much bigger role.
A new cancer diagnosis technique that separates cancerous cells from blood may inspire a new form of treatment for the disease. A researcher at Australia's University of New South Wales (UNSW)who helped devise the test says it could potentially be scaled up to cleanse meaningful quantities of blood, which could then be reintroduced into the body to battle different forms of the disease.
Scientists from Oregon State University have developed a new delivery system for cancer treatment that attacks the condition simultaneously with three different drugs. According to the team, it's likely to prove particularly effective against cancers that spread through the lymphatic system, such as metastatic melanoma.