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Blood

Micrograph of endothelial tissue grown from blood-derived pluripotent stem cells

There are ongoing moral and ethical battles concerning the farming and application of human embryonic stem cells in medical research and applications. Without judging any of the viewpoints represented in the fracas, it is clear that the stem cell world would be a friendlier place if the harvesting of embryonic stem cells were not necessary. Toward this goal, Johns Hopkins scientists have developed a reliable method to turn the clock back on blood cells, restoring them to a primitive stem cell state from which they can then develop into any other type of cell in the body.  Read More

The HemoGlobe promises to provide an inexpensive way to detect anemia in the developing wo...

A terrible scourge in the developing world, anemia claims hundreds of thousands of lives every year. Medical tests to detect the condition and prevent tragedy are often unavailable, but students at John Hopkins University have invented a sensor that turns a cell phone into an inexpensive blood analysis tool. At an awards ceremony in Seattle on July 14, the bioengineernig undergraduates revealed their device, the HemoGlobe, which will soon be undergoing testing in Africa.  Read More

Scientists have had success in tracking the passage of blood cells within the body, by lab...

Thanks to advances in stem cell therapy, it is now possible to use engineered white blood cells to fight diseases such as HIV within the human body. When such treatments are being developed, however, it can be difficult to track where the introduced cells travel within a patient’s system, and how many of them make it to their target. Now, thanks to research being carried out at the University of Edinburgh's Centre for Cardiovascular Science, those cells can be magnetically labeled.  Read More

Engineered microvessels can form bends and T-junctions, like this one. The blue dots are t...

A team of bioengineers at the University of Washington has developed the first structure for growing small human blood vessels in the laboratory. The vessels behave remarkably like those in a living human and offer a better and much more modular approach to studying blood-related diseases, testing drugs and, one day, growing human tissues for transplant.  Read More

The experimental microfluidic device, which could find use in the cleansing of infected bl...

In a natural phenomenon known as margination, platelets and leukocytes (white blood cells) within the bloodstream move towards the sides of blood vessels and adhere to them. It occurs at wound sites, during the early stages of inflammation. Recently, a team of researchers from the Massachusetts Institute of Technology and the National University of Singapore have put that process to work in a microfluidic device that could be used to cleanse the blood, perhaps acting as a treatment for bacteria-related blood disorders such as sepsis.  Read More

New findings have identified a blood test which could predict heart attack or stroke weeks...

Roughly two and a half million Americans suffer a heart attack or a stroke each year. About 20% of these - half a million people - die in the aftermath. The proximate cause for both heart attack and stroke is a blood clot in the wrong place - a blood clot that could be prevented or minimized by anti-clot therapy IF physicians knew that an attack or stroke was expected shortly. New findings from a research study led by Scripps Translational Science Institute (STSI) has identified a new blood test which has the promise of predicting heart attack or stroke weeks prior to their occurrence.  Read More

One of Fraunhofer's artificial venous valves

Chronic venous insufficiency - or CVI - is a very common medical condition in which veins in the legs cannot pump enough oxygen-poor blood back to the heart. It is caused by faulty valves within the leg veins, and causes blood to pool in the legs, which can lead to edemas and even open ulcers. Typically, treatment consists of anti-inflammatory drugs and diuretics, along with the use of items such as compression stockings. Now scientists have developed a method of mass-producing artificial venous valves, that could replace the malfunctioning natural ones.  Read More

University of Tennessee researchers have invented a device that instantly detects diseases...

Infectious diseases these days seem to have gotten a lot of attention, with media hype and threats of pandemics often being portrayed in apocalyptic sci-fi movies. We all know that several types of these diseases can spread rapidly, and it is crucial that doctors be able to identify them quickly in order to prevent an epidemic. Unfortunately, current testing methods can take hours and even days, delaying the process of adequate prevention. It should then ease your mind to hear that researchers at the University of Tennessee have invented a device that can rapidly detect these unwanted afflictions.  Read More

The MinION is the size of a USB memory stick, and obtains both power and computer analysis...

At the Advances in Genome Biology and Technology 2012 conference (AGBT), Oxford Nanopore Technologies Ltd. announced it is entering the gene-sequencing battle with a disposable DNA sequencer that will sell for under $900 in the second half of 2012. The USB-size sequencer is called the MinION (min-ion), and has already demonstrated the potential to bring genome sequencing and personalized medicine out of the lab and into physicians’ offices.  Read More

A depiction of glucose molecules moving across the surface of a plasmonic interferometer

In order to measure their blood glucose levels, most diabetics must perform painful finger-prick tests on a daily basis. Hopefully, however, that may not always be the case. Scientists at Rhode Island’s Brown University are now developing a biochip, that could someday be used to assess the concentration of glucose molecules in a tiny sample of saliva.  Read More

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