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Biomarkers

The new ultra-sensitive biosensor has been demonstrated by detecting very small concentrat...

A new ultra-sensitive test developed by scientists from the Imperial College London and Spain’s University of Vigo has the potential to detect the earliest stages of a disease, thereby giving any treatment the best possible chance of succeeding. The researchers claim their new biosensor test is capable of detecting biomarkers (molecules which indicate the presence of a disease) at concentration levels much lower than is possible with existing biosensors. While the new test has already proven capable of detecting a biomarker associated with prostate cancer, the team says their biosensor could be easily reconfigured to detect biomarkers related to other diseases or viruses.  Read More

New findings have identified a blood test which could predict heart attack or stroke weeks...

Roughly two and a half million Americans suffer a heart attack or a stroke each year. About 20% of these - half a million people - die in the aftermath. The proximate cause for both heart attack and stroke is a blood clot in the wrong place - a blood clot that could be prevented or minimized by anti-clot therapy IF physicians knew that an attack or stroke was expected shortly. New findings from a research study led by Scripps Translational Science Institute (STSI) has identified a new blood test which has the promise of predicting heart attack or stroke weeks prior to their occurrence.  Read More

The lower right red dot indicates that this CHEMCARD paper test is ready (Photo: Scott T. ...

Throughout the world, reactive paper-based systems are used to test peoples’ blood, urine and other bodily fluids for biomarkers that indicate everything from diabetes to pregnancy. Such systems are also used to detect pollution in water. However, for many of these tests to be accurate, an exact amount of time must pass between the application of the fluid and the viewing of the paper – if the paper is observed any earlier or later, the perceived results could be inaccurate. People typically use stopwatches to avoid this problem, but not everyone in the world has access to such devices, so scientists from Pennsylvania State University (PSU) have developed a simple timer that can be built into the paper itself.  Read More

Biomedical engineer Brian Lithgow and a model showing the 'tilt chair' and electrode techn...

Central Nervous System (CNS) disorders such as depression, schizophrenia and Attention Deficit Hyperactivity Disorder (ADHD) cost upwards of US$2 trillion globally every year and affect one in four people in their lifetime. At present, diagnosing these conditions relies on an often unreliable process of questions and interviews, which means it can take many years for sufferers to be correctly diagnosed. A new diagnostic technique that measures the patterns of electrical activity in the brain’s vestibular (or balance) system could dramatically fast-track the detection of mental and neurological illnesses.  Read More

Lead researchers Shana Kelley and Ted Sargent with the cancer detecting microchips

Because the signature biomarkers that indicate the presence of cancer at the cellular level are generally present only at low levels in biological samples, detecting them is a procedure that usually takes days and involves a room filled with computers. Now researchers have used nanomaterials to develop a microchip small enough to fit in a device the size of a mobile phone, and sensitive enough to do the job in 30 minutes.  Read More

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