Highlights from the 2014 LA Auto Show

Alzheimer's Disease

Researchers in the UK have found that an eye tracking measurement test can help detect ear...

As researchers look for better ways to diagnose Alzheimer’s disease in its early stages, one promising detection methodology to emerge is a simple eye tracking procedure developed by scientists at Lancaster University in conjunction with Royal Preston Hospital. The results of such tests can help flag initial signs of memory impairment that are associated with the onset of the disease.  Read More

Researchers have found to block pathological aggression in mice that could lead to new tre...

“Don’t make me angry. You wouldn’t like me when I’m angry,” the Hulk’s alter ego Bruce Banner famously said. Now researchers have made a discovery that might one day have implications for anyone considering Bruce as a potential house guest. The researchers have identified a brain receptor that malfunctions in overly hostile mice - a receptor that also exists in humans - and found a way to shut it down, offering the potential for the development of treatments for severe aggression.  Read More

A new marker of Alzheimer's disease can predict how rapidly a patient's memory and other m...

A new marker of Alzheimer’s disease can predict how rapidly a patient’s memory and other mental abilities will decline after the disorder is diagnosed, according to researchers at Washington University School of Medicine in St. Louis. Just released in Neurology were the results of a three-year long study that followed 60 patients with early Alzheimer's disease. The study found that rapid mental decline was predicted by the presence of larger levels of visinin-like protein 1 (VILIP-1) in the spinal fluid.  Read More

Maintaining sugar levels in a brain protein known as tau could slow or prevent Alzheimer's...

We’ve reported on numerous different approaches by scientists looking to tackle Alzheimer’s disease. While some, such as the anticancer drug bexarotene and a compound known as J147, show great promise, there is still no approved treatment to slow the disease’s progression. The latest promising candidate for a treatment comes from Canada’s Simon Fraser University (SFU), where a team has concluded that ensuring that sugar levels in a brain protein known as tau are maintained could slow or prevent the fatal disease.  Read More

An anticancer drug, bexarotene, reverses the physical and cognitive effects of Alzheimer's...

Studies of the anticancer drug bexarotene have shown that, in mice, the drug quickly reverses the physiological, cognitive, and memory deficits which are characteristic of Alzheimer's. More than half of the amyloid beta plaques associated with Alzheimer's were cleared from the brain within hours, and normal behavioral patterns which had been blocked by the plaques were restored within 72 hours.  Read More

A new compound, J147, could be the first drug capable of halting the progression of Alzhei...

Anyone who has watched as Alzheimer’s disease robs a friend or family member of their memories and faculties before ultimately claiming their life knows just what a truly horrible disease it is. According to the World Health Organization, it is the fourth leading cause of death in high-income countries and, due to an aging worldwide population, it is predicted to affect one in 85 people worldwide by 2050 – unless a treatment can be found. Scientists at the Salk Institute for Biological Studies have high hopes for a new drug they have developed that has improved memory and prevented brain damage in mice and is a promising candidate for the first drug capable of halting the progression of Alzheimer’s in humans.  Read More

The GPS Shoes allow real-time tracking of the wearer

As millions of baby boomers approach 65, the rates of Alzheimer’s sufferers is expected to continue to rise significantly in the coming decade. Already 5.4 million Americans are living with the disease with that figure predicted to rise to as many as 16 million by 2050, according to the Alzheimer’s Association. To make it easier for caregivers and family members to keep track of those suffering dementia, Personal Location Services company GTX Corp has partnered with comfort shoe manufacturer Aetrex to produce the GPS Shoe that allows real-time tracking of the wearer.  Read More

By duplicating the interaction between divisions in the brain responsible for long-term me...

Using electrical probes embedded into the brains of rats, scientists have managed to replicate the brain function associated with long-term behavior and found a way to literally turn memories on and off with the flip of a switch. The scientists hope their research will eventually lead to a neural prosthesis to help people suffering Alzheimer’s disease, the effects of stroke or other brain injury to recover long-term memory capability.  Read More

A new tool for researching neurodegenerative diseases such as Alzheimer's takes its inspir...

In order to detect the presence of nearby females, the male silk moth utilizes an oily coating on his antennae. Any female pheromone molecules that are in the air will stick to that coating, which then guides them through nanotunnels in the insect's exoskeleton, and ultimately to nerve cells that alert Mr. Moth to the fact that there are ladies in the area. It's a clever enough system that scientists from the University of Michigan have copied it, in hopes of better understanding neurodegenerative diseases such as Alzheimer's.  Read More

Scientists have for the first time created "super twisted" light which can be used for more effective disease and virus identification. The process involves polarizing a light beam to create a kind of light corkscrew, then reflecting it off a gold surface to twist the vortex even tighter. Alzheimer’s and Parkinson’s disease are two conditions now being examined using this new technique.  Read More

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