Introducing the Gizmag Store

Alzheimer's Disease

Testing the prototype system (Photo:Tecnalia)

The Tecnalia Centre for Applied Research has created a system of sensors which when fitted in a home can monitor changes in a person's habits and routine. These observations can then be used to assess whether an individual is suffering from the early stages of a neurodegenerative disease such as Alzheimer's.  Read More

Alzheimer's disease gradually destroys the brain and its function (Photo: US National Inst...

US medical researchers have developed a blood test which predicts with 90 percent accuracy if an individual will develop Alzheimer's disease or mild cognitive impairment within three years. The test, which looks for a set of ten lipid markers, will allow treatments to be sought that may be effective during this early, asymptomatic stage of the disease.  Read More

A compound commonly found in fruit and vegetables, including apples, grapes and strawberri...

Alzheimer's disease represents the most common form of dementia, with the early stages of the disease generally characterized with short term memory loss and learning difficulties that increase in severity as the patient progresses in age. Scientists at the Salk Institute for Biological Studies, California, have discovered that with regular treatments of the antioxidant fisetin, they were able to prevent memory loss in mice with genetic mutations linked to Alzheimer's.  Read More

Drugs called 'pharmacoperones' can fix the problems that occur when proteins 'misfold'

Proteins adopt their functional three-dimensional structure by the folding of a linear chain of amino acids. Gene mutation can cause this folding process to go awry, resulting in "misfolded" proteins that are inactive or, in worse cases, exhibit modified or toxic functionality. This is the cause of a wide range of diseases, but researchers have developed a technique that fixes these misfolded proteins, allowing them to perform their intended function, thereby providing a potential cure for a number of diseases.  Read More

According to researchers, a multi-photon laser technique can be used to detect protein agg...

It is generally believed that aggregations of proteins are responsible for brain disorders such as Alzheimer's, Parkinson's and Creutzfeldt-Jakob disease. However, the difficulty has been in detecting the aggregates responsible and removing them from the brain. Researchers at Chalmers University of Technology in Sweden and Polish Wroclaw University of Technology have found a potential solution using lasers.  Read More

Scientists have successfully used accelerometers to determine whether or not a person is s...

Among the behavioral symptoms of Alzheimer's, one of the most prominent is a change in the "temporal structure of activities" – in other words, the amount of time that it takes the patient to do things. With that in mind, German scientists have developed a new early detection method that involves attaching accelerometers to patients, in order to assess their movements.  Read More

New research has provided 'strong hope' of finding a drug to combat Alzheimer’s (Image: Sh...

A team of researchers at Yale University has completed a molecular model for Alzheimer's disease by identifying a protein that plays a key role in its onset. Promisingly, the study showed that when the activity of this protein is blocked by an existing drug, mice engineered as models for human AD recover their memories.  Read More

New hope could be on the way in the search for a treatment for Alzheimer's disease (Image:...

Although no one is announcing a cure for Alzheimer’s disease just yet, research recently conducted at the University of Southern California does at least offer a glimmer of hope. Using drugs known as TSPO (translocator protein) ligands, scientists there have successfully halted and even reversed the effects of Alzheimer’s in mice.  Read More

One of the test mice, and a live video feed of its fluorescing neurons

What’s that mouse thinking about? Scientists at California’s Stanford University can now tell you – to a limited extent. They recently had success in imaging the neural activity of mice, in real time. While the ability to “read a mouse’s mind” may not fire many peoples’ imaginations, the technology could prove very useful in researching diseases like Alzheimer's.  Read More

VTT researchers will spend the next five years carrying out the test at memory clinics in ...

Scientists at VTT Technical Research Centre in Finland have developed new software called PredictAD that could significantly boost the early diagnosis of Alzheimer's disease.  Read More

Looking for something? Search our 26,500 articles