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Alzheimer's Disease

Researchers have discovered specific genetic variants that could delay the onset of Alzhei...

Over the past few years scientists and researchers have made some inroads in the fight against Alzheimer’s disease, but as yet no definitive cure has been found. In the latest promising development, a team of Canadian researchers has identified a genetic variant that can delay the onset of the disease by up to four years.  Read More

In addition to early detection, it is hoped that the new blood test will lead to significa...

An international collaboration of scientists led by King's College London (KCL) and Proteome Sciences plc has identified a combination of 10 proteins found in human blood cells which may lead to an accurate early warning test for Alzheimer's. An increased ability to detect this debilitating disease at an early stage has the potential to greatly improve quality of life and may even lead to new clinical trials developing new avenues of treatment designed to stop the disease in its tracks.  Read More

Our Big Box is a new website designed to help improve the psychological health of dementia...

Dementia charity The Memory Box Network has launched a new website to help improve the well-being of dementia sufferers. Our Big Box is a "digital treasure chest" to which memorable photos can be saved. It is aimed at improving psychological health by stimulating reminiscence and interaction.  Read More

An infusion of blood from young mice has led to cognitive improvements in older mice (Phot...

A literal infusion of some "young blood" has the ability to turn back the clock and restore the mental capabilities of old mice, according to a study conducted by researchers at the Stanford University School of Medicine. If similar results are seen in humans, the simple technique could lead to new treatments for forms of dementia, such as Alzheimer's disease.  Read More

Testing the prototype system (Photo:Tecnalia)

The Tecnalia Centre for Applied Research has created a system of sensors which when fitted in a home can monitor changes in a person's habits and routine. These observations can then be used to assess whether an individual is suffering from the early stages of a neurodegenerative disease such as Alzheimer's.  Read More

Alzheimer's disease gradually destroys the brain and its function (Photo: US National Inst...

US medical researchers have developed a blood test which predicts with 90 percent accuracy if an individual will develop Alzheimer's disease or mild cognitive impairment within three years. The test, which looks for a set of ten lipid markers, will allow treatments to be sought that may be effective during this early, asymptomatic stage of the disease.  Read More

A compound commonly found in fruit and vegetables, including apples, grapes and strawberri...

Alzheimer's disease represents the most common form of dementia, with the early stages of the disease generally characterized with short term memory loss and learning difficulties that increase in severity as the patient progresses in age. Scientists at the Salk Institute for Biological Studies, California, have discovered that with regular treatments of the antioxidant fisetin, they were able to prevent memory loss in mice with genetic mutations linked to Alzheimer's.  Read More

Drugs called 'pharmacoperones' can fix the problems that occur when proteins 'misfold'

Proteins adopt their functional three-dimensional structure by the folding of a linear chain of amino acids. Gene mutation can cause this folding process to go awry, resulting in "misfolded" proteins that are inactive or, in worse cases, exhibit modified or toxic functionality. This is the cause of a wide range of diseases, but researchers have developed a technique that fixes these misfolded proteins, allowing them to perform their intended function, thereby providing a potential cure for a number of diseases.  Read More

According to researchers, a multi-photon laser technique can be used to detect protein agg...

It is generally believed that aggregations of proteins are responsible for brain disorders such as Alzheimer's, Parkinson's and Creutzfeldt-Jakob disease. However, the difficulty has been in detecting the aggregates responsible and removing them from the brain. Researchers at Chalmers University of Technology in Sweden and Polish Wroclaw University of Technology have found a potential solution using lasers.  Read More

Scientists have successfully used accelerometers to determine whether or not a person is s...

Among the behavioral symptoms of Alzheimer's, one of the most prominent is a change in the "temporal structure of activities" – in other words, the amount of time that it takes the patient to do things. With that in mind, German scientists have developed a new early detection method that involves attaching accelerometers to patients, in order to assess their movements.  Read More

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