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Aging

A new compound, J147, could be the first drug capable of halting the progression of Alzhei...

Anyone who has watched as Alzheimer’s disease robs a friend or family member of their memories and faculties before ultimately claiming their life knows just what a truly horrible disease it is. According to the World Health Organization, it is the fourth leading cause of death in high-income countries and, due to an aging worldwide population, it is predicted to affect one in 85 people worldwide by 2050 – unless a treatment can be found. Scientists at the Salk Institute for Biological Studies have high hopes for a new drug they have developed that has improved memory and prevented brain damage in mice and is a promising candidate for the first drug capable of halting the progression of Alzheimer’s in humans.  Read More

The even distribution of different cell types seen in the intestinal tissues of young frui...

Caloric restriction has been shown to slow the signs of aging and delay the development of age-related diseases in a wide range of animals. However, scientists have been unable to explain just why limiting daily food intake has such a beneficial effect on health and the biological mechanisms that underlie the phenomenon. Researchers in Sweden recently claimed to have unlocked a piece of the puzzle by identifying one of the enzymes that appears to play a major role in the process and now another group in the U.S. has provided another clue by tweaking a gene in fruit flies and extending their lifespan by as much as 50 percent.  Read More

The Top 10 things you CAN'T have for Christmas 2011

With Christmas fast approaching it means it's time for our annual look back at some of the technology that caught our eye and had us wishing our fortunes didn't match that of the Greek economy. While not all of the items on this list can be had for an extremely large wad of cash, those that are available for purchase will only find their way down the chimneys of those with a lottery winning or ultra-wealthy - and ultra-generous - family member or friend. Still, Christmas is a time for miracles so it is in that spirit that Gizmag presents its 2010 top 10 list of things you can't have for Christmas this year.  Read More

Memo Touch tablet comes with software that provides memory-challenged aging users with vir...

While most of the newest tech products are marketed at youngsters or people of working age, there's an increasing number of gadgets aimed at senior users as well. A case in point is the recently introduced Memo Touch tablet, which is based on a 10-inch Archos 101 tablet and comes with custom software that provides memory-challenged aging users with virtual assistance to help them deal with everyday activities and it allows caregivers to update content remotely.  Read More

Restricting calorie intake has been shown to delay the aging process and the enzyme Prx1 h...

Studies have shown that restricting the intake of calories without reducing the intake of vitamins and minerals slows the signs of aging in a wide range of animals including monkeys, rats and fish, and even some fungi. More recent studies provide evidence that calorie restriction can also have the same effect on humans and now researchers at the University of Gothenburg have identified one of the enzymes they claim plays a major role in the aging process.  Read More

Scientists have reversed the aging process in human adult stem cells, which are in turn re...

By now, most people are probably aware of the therapeutic value of stem cells, as they can become any other type of cell in the human body. One of their main duties, in fact, is to replace those other cells as they degrade. Once people reach an advanced age, however, even the stem cells themselves start to get old and nonfunctional - when the cells that are supposed to replace the other cells can't do their job anymore, age-related tissue problems start occurring. A team of researchers from the Buck Institute for Research on Aging in collaboration with the Georgia Institute of Technology, however, may be on the way to solving that problem. They have succeeded in reversing the aging process in human adult stem cells.  Read More

A new study raises questions about one of the favored theories of aging involving increasi...

A recent study suggests that, at least for worms, free radicals may not be the "bad guys" after all. It turns out that if you are a bacteria-eating worm of the species C. elegans, genetic modifications that raise your free radical levels don't have the negative effect expected, but instead serve to lengthen lifespan.  Read More

Nylstar has developed a new nanomaterial that is claimed to have moisturizing, protective ...

For as long as I can remember, keeping skin young and fresh has generally involved the liberal application of various moisturizing and nourishing creams with strange-sounding ingredients and an even greater number of anti-aging claims. Spain's Nylstar has managed to bind an important component of skin with 24K gold at a nanoscale level to create NYG nanoparticles. The new nanomaterial is then integrated with nylon fibers to make something called Nylgold dermawear, which is said to have a nourishing and protective effect on the skin of the wearer.  Read More

Chromosomes, with their telomere caps highlighted. Looking after these telomeres could be ...

The aging process - it's undignified, unwanted, and many would say unnecessary. After all, the cells in your body are constantly replacing themselves - why can't they do it without causing progressive degradation of organs that lead to discomfort, weakness and death? Well, perhaps they can. Harvard scientists have discovered that by controlling certain genetic processes in mice, they can not only slow down the aging process, but "dramatically" reverse it throughout the body. It's a massive discovery, but it won't be able to be used in humans yet without some pretty scary consequences.  Read More

An illustration of a telomerase molecule (Image: Sierra Sciences, LLC)

For many scientists who know about such things, the question isn’t whether the first person to live forever has been born, but how old they are. The basis for this belief is that, if a person can survive the next 20 or 30 years, then breakthroughs in biotechnology will easily allow them to extend their lifespan – not to mention their quality of life – to 125 years. From that point, the advances will keep coming to allow the prolonging of life indefinitely. One of the first steps towards such a reality has just been announced by a group of researchers who have discovered the first compound that activates an enzyme called telomerase in the human body.  Read More

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