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Aging

Biology

Telomere-lengthening procedure turns clock back years in human cells

Researchers at the Stanford University School of Medicine have developed a new procedure to increase the length of human telomeres. This increases the number of times cells are able to divide, essentially making the cells many years younger. This not only has useful applications for laboratory work, but may point the way to treating various age-related disorders – or even muscular dystrophy. Read More

Medical

Lifespan of fruit flies prolonged by selecting best cells in the body

Using a technique in which better cells in the body to be selected at the expense of more damaged ones, researchers at the University of Bern in Switzerland have managed to significantly increase the lifespan of the common fruit fly. Although most people would like to see flies living shorter, not longer lives, the development could have implications for increasing the lifespan of humans.Read More

Health & Wellbeing

Scientists developing drug that could prevent sun-related aging of skin

Excessive exposure to sunlight is the leading cause of skin deterioration, causing it to age prematurely. We need some exposure, however, in order to synthesize vitamin D – plus who wants to stay in the shade all the time? Using a good sunscreen definitely helps, although scientists from the University of British Columbia are taking things a step farther – they're developing a drug that could ultimately prevent the sunlight-related aging of skin. Read More

Medical

Activating gene in key organ systems slows aging process throughout the body

With a typical lifespan of around six weeks, the common fruit fly is one animal that could benefit from a slowing of the aging process. And that's just what a team of biologists at UCLA have achieved by activating a gene called AMPK. Possibly of more interest to us higher life forms is the researchers' belief that the discovery could help delay aging and age-related diseases in humans.Read More

Medical

Harvard researchers find protein that could reverse the aging process

Researchers from the Harvard Stem Cell Institute (HSCI) have shown that injections of a protein dubbed GDF11, when administered to older mice, appear to cause a reversal of many signs of aging. Analysis showed that every major organ system tested displayed signs of improvement, with the protein even appearing to reverse some of the DNA damage which is synonymous with the aging process itself. Read More

Medical

Recharging aging brains could be in the (young) blood

A literal infusion of some "young blood" has the ability to turn back the clock and restore the mental capabilities of old mice, according to a study conducted by researchers at the Stanford University School of Medicine. If similar results are seen in humans, the simple technique could lead to new treatments for forms of dementia, such as Alzheimer's disease.Read More

Science

Cause of aging reversed in mice: Human trials may start next year

With the wide-ranging benefits of reducing disease and enabling a longer, healthier life, reversing the causes of aging is a major focus of much medical research. A joint project between the University of New South Wales (UNSW) in Australia and Harvard Medical School that restored communication within animal cells has the potential to do just that, and maybe more. With the researchers hoping to begin human clinical trials in 2014, some major medical breakthroughs could be just around the corner.Read More

Health & Wellbeing

Partial gene knockout produces long-lived mice

Researchers at the National Institutes of Health have found that suppressing the expression of a single gene in mice extends their average lifespan by about 20 percent – the equivalent of humans living an average of 95 years. While modification of the so-called mTOR gene may not lead to the fountain of youth, further study could open up a path to keeping us healthier and more alert in our old age.Read More

Health & Wellbeing

New drug mimics the beneficial effects of exercise

A drug known as SR9009, which is currently under development at The Scripps Research Institute (TSRI), increases the level of metabolic activity in skeletal muscles of mice. Treated mice become lean, develop larger muscles and can run much longer distances simply by taking SR9009, which mimics the effects of aerobic exercise. If similar effects can be obtained in people, the reversal of obesity, metabolic syndrome, and perhaps Type-II diabetes might be the very welcome result.Read More

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