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Aging

A protein that's more abundant in young mice appears to reverse the aging process in older...

Researchers from the Harvard Stem Cell Institute (HSCI) have shown that injections of a protein dubbed GDF11, when administered to older mice, appear to cause a reversal of many signs of aging. Analysis showed that every major organ system tested displayed signs of improvement, with the protein even appearing to reverse some of the DNA damage which is synonymous with the aging process itself.  Read More

An infusion of blood from young mice has led to cognitive improvements in older mice (Phot...

A literal infusion of some "young blood" has the ability to turn back the clock and restore the mental capabilities of old mice, according to a study conducted by researchers at the Stanford University School of Medicine. If similar results are seen in humans, the simple technique could lead to new treatments for forms of dementia, such as Alzheimer's disease.  Read More

By restoring communication between a cell’s mitochondria (shown here from a mammalian lung...

With the wide-ranging benefits of reducing disease and enabling a longer, healthier life, reversing the causes of aging is a major focus of much medical research. A joint project between the University of New South Wales (UNSW) in Australia and Harvard Medical School that restored communication within animal cells has the potential to do just that, and maybe more. With the researchers hoping to begin human clinical trials in 2014, some major medical breakthroughs could be just around the corner.  Read More

HIH researchers have found that suppressing the expression of a single gene in mice extend...

Researchers at the National Institutes of Health have found that suppressing the expression of a single gene in mice extends their average lifespan by about 20 percent – the equivalent of humans living an average of 95 years. While modification of the so-called mTOR gene may not lead to the fountain of youth, further study could open up a path to keeping us healthier and more alert in our old age.  Read More

The Scripps Research Institute has developed a drug that duplicates the benefits of exerci...

A drug known as SR9009, which is currently under development at The Scripps Research Institute (TSRI), increases the level of metabolic activity in skeletal muscles of mice. Treated mice become lean, develop larger muscles and can run much longer distances simply by taking SR9009, which mimics the effects of aerobic exercise. If similar effects can be obtained in people, the reversal of obesity, metabolic syndrome, and perhaps Type-II diabetes might be the very welcome result.  Read More

GiraffPlus is an assisted living system for the elderly

GiraffPlus is an EU-funded project that uses telepresence technology to monitor the elderly in their own homes. The system has already been tested in a demo apartment in Örebro, Sweden. Now GiraffPlus is being taken further afield to be tested in real homes in Sweden, Italy and Spain.  Read More

The small almond-sized portion of the brain known as the hypothalamus could be the body's ...

Instead of traipsing through Florida in search of the Fountain of Youth, Spanish explorer Juan Ponce de León might have been better off turning his search inwards. More specifically, he should have turned his attention to a region of the brain called the hypothalamus. At least that’s what research carried out on mice by scientists at New York’s Albert Einstein College of Medicine of Yeshiva University suggests. They found that the hypothalamus controls many aspects of aging, opening up the potential to slow down the aging process by altering signal pathways within that part of the brain.  Read More

Seniors who played the Road Tour video game reportedly experienced an improvement in their...

It’s a sad fact of life that as we age, our cognitive skills decline. In particular, the “executive function” of our mind diminishes – this function is a key aspect of our memory, attention, perception, and problem solving skills. There may be help, however. Scientists from the University of Iowa are now claiming that by playing a specific video game, test subjects aged 50 and over were able to stop and even reverse the trend.  Read More

The SIRT3 protein molecule that appears to play a central role in regulating aging and lon...

The quest for longer and healthier life, if not immortality, has been part of the human experience since we evolved the ability to recognize the total annihilation of individual death. Our understanding of the biology of aging at the molecular level is advancing so rapidly that it appears inevitable that another decade or two of life will be enabled before long. A new step in what may be the right direction has just been published by researchers at the University of California, Berkeley.  Read More

Researchers have found that oxygen-containing free radicals aid rather than harm cell rege...

Researchers at the University of Manchester have found that Reactive Oxygen Species (ROS) – oxygen-containing free radicals that are commonly believed to be harmful to cells – actually play a vital role in the regeneration of the tails of tadpoles. The finding could have profound implications for the healing and regeneration of human tissue.  Read More

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