Starting with one mouse, scientists create 581 successive clones
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Dolly the first cloned mammal (Photo: Toni Barros via Wikipedia CC 2.0)
Dr. Wakayama's modified somatic cell nuclear transfer approach toward serial cloning of mice (Photo: Riken)
Dr, Wakayama's cloning laboratory (Photo: Riken)
Mouse clones from the 24th and 25th generation of serial cloning (Photo: Riken)
Article Summary
Using the technique that created Dolly the sheep, researchers from the RIKEN Center for Developmental Biology in Kobe, Japan, have identified a way to produce healthy mouse clones that live a normal lifespan and can be sequentially cloned indefinitely. In an experiment that started in 2005, the team led by Dr. Teruhiko Wakayama has used a technique called somatic cell nuclear transfer (SNCT) to produce 581 clones of one original "donor" mouse through 25 consecutive rounds of cloning.
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