Blood vessels within a microvascular construct, covering an implanted device
Researchers at the University of Louisville/Jewish Hospital's Cardiovascular Innovation Institute (CII) have discovered a method for preventing scar tissue from forming around implantation devices. This discovery could have a great impact on the functionality of common implanted devices, such as pacemakers, chemotherapy ports and glucose sensors. According to the study, if a unique system of blood vessels is created to interact with local tissue around an implanted device, better long term results can be achieved. The process involves “pre-vascularizing” a device prior to implantation, using what the team call a microvascular construct (MVC), which consists of blood vessels contained within a collagen gel. The idea is that a device will be coated in this gel prior to implantation. Since the body’s natural process is to find a foreign object and form a scar around it, this new study could prevent this problem from occurring.