New nanoparticle delivery device designed for gene therapy

Scientists from Ohio State University (OSU) have created a nanoparticle that can deliver DNA deeply enough into a cell to allow genetic material to be activated. This is a key step in gene therapy, the “reprogramming” of defective genes. Previously, scientists have used deactivated viruses for this task, but have been limited by the body’s immune system attacking those viruses. Nanoparticle delivery is reportedly two-and-a-half to ten times more effective, because it generates much less of an immune response.

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