Microneedles used to deliver live dried vaccines through the skin
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The microneedle arrays in their silicone molds
The arrays were made up of sucrose mixed with a dried version of a live modified adenovirus-based candidate HIV vaccine
Scientists have used microneedle arrays to store a live vaccine at room temperature, and administer it through the skin of lab mice
Article Summary
While it’s vitally important to bring vaccines for diseases such as tuberculosis to developing nations, getting them there is only part of the challenge. Because these countries often have unreliable infrastructures, it’s entirely possible that the vaccines can’t consistently be kept as cold as is required. As a result, they could be rendered ineffective. Now, however, scientists from King’s College London have succeeded in containing a dried live vaccine in a microneedle array, that doesn’t need to be refrigerated.
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