Molecule that can erase or restore long-term memories – in rats

If you’re struggling to remember the names of classmates from high school, or just can’t forget that time you made a complete ass of yourself in front of your high school crush, then a single molecule known as PKMzeta could be to blame – and increasing or decreasing its activity in the brain could either help you remember those names that seem on the tip of your tongue or drive that embarrassing memory from your head. In a new study, researchers have demonstrated that a memory in rats can either be enhanced or erased long after it is formed by manipulating the activity of the brain enzyme PKMzeta.

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