Scientists at Brown University have developed a new drug delivery system to safely hold a magnetic gelatin capsule in place anywhere in the gastrointestinal tract of a rat; in humans, it could improve drug delivery and pharmacological research
Many people take pills to help manage or cure serious illness, and some of these life-saving drugs can only be absorbed in very specific parts of the intestine. The problem with oral administration is that pills often don’t dissolve at exactly the right site in the gastrointestinal tract where medicine can be absorbed into the bloodstream. A new drug delivery system developed by scientists at Brown University uses a magnetic gelatin capsule and an external magnet that can precisely sense the force between it and the pill and vary that force, as needed, to hold the pill in place. The team has successfully used the technology with rats and in future it could provide a new way to deliver many drugs to humans, including those with cancer or diabetes.