Light stimulation could restore movement to paralyzed limbs

In a study that could eventually restore movement to humans’ paralyzed limbs, researchers at California’s Stanford University have used light to induce muscle contractions in mice. A gene derived from algae was inserted into the mice, encoding a light-sensitive protein which adhered to their nerve cell surfaces. Scientists then placed an “optical cuff” lined with tiny, inwards-facing LEDs around the mice’s sciatic nerves. By penetrating those nerves with brief, high-intensity bursts of blue light, they were able to produce muscle contractions similar to those that would occur naturally. The technology is called “optogenetics.”

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