A new technique uses light to differentiate between healthy (top) and misshapen (bottom) red blood cells within a sample
Ordinarily, red blood cells should look like a disc with a medium-sized dimple on the top and bottom. If that dimple is either too large or too small, it can indicate the presence of a disease such as sickle cell anemia or malaria. Pathologists traditionally have had to examine blood samples under a microscope, manually looking for these misshapen cells. A new technique developed at the University of Illinois at Urbana-Champaign, however, uses light to automatically detect such cells within seconds.