New drugs promise two days without sleep and improved alertness and cognitive powers

March 5, 2007 Two years ago, we wrote about the “time-shifting” drug, Modafinil that enables you to stay awake for 40+ hours with close to full mental capacity and with few side effects. The drug is a eugeroic and offers improved memory, mood enhancement, improved alertness and cognitive powers, and has a much smoother feel than amphetamines because they work differently. Popular Science is now reporting that we’re just about to see new forms of super eugeroic called armodafinil (Modafinil’s creator Cephalon is awaiting FDA approval for the drug), and a drug code-named CX717 from Cortex. Both drugs promise even longer periods of wakefulness, and in experiments with Ampakine CX717, sleep-deprived rhesus monkeys on the drug often outperformed their own well-rested but undrugged best efforts on mental-performance tests. While these drugs will be marketed to assist people with sleep disorders like narcolepsy, it’s their potential as recreational and workplace performance-enhancing drugs that make them worth watching. The times they are a changing …

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