It may be possible to treat depression without drugs, by electrically stimulating the trigeminal nerve via external or subcutaneous electrodes (Image: NeuroSigma)
The anterior cingulate and prefrontal cortex (red) and frontal gyrus (orange) areas of the brain, which eTNS is said to activate (Image: NeuroSigma)
The World Health Organization has projected that by 2020, major depression will be the second-most significant cause for disability in the world, after heart disease. Along with psychotherapy, the disorder is usually treated using antidepressant drugs. There is often a frustrating trial-and-error period involved in finding the right drug for the right person, however, while side effects can include obesity, sexual dysfunction, and fatigue ... to name a few. Los Angeles-based company NeuroSigma is now looking into an alternative drug-free therapy, that could ultimately incorporate electrodes implanted under the patient’s skin.
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