New chemical reagent turns biological tissue transparent
A three-dimensional reconstruction of neurons expressing yellow fluorescent protein in a mouse's cerebral cortex and hippocampus, obtained using Scale
Article Summary
Scientists are constantly looking for new and better ways of seeing through biological tissue, in order to see cells within it that have been marked with dyes, proteins or other substances. While recent research has involved using marking materials such as carbon nanotubes and firefly protein, scientists from Japan’s RIKEN Brain Science Institute have taken a different approach – they’ve developed a chemical reagent that causes the tissue surrounding the marked cells to become transparent.
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