A chemical that affects the biological clock could help provide a new class of drugs to treat diabetes (Image: Nicole Oliver, UC San Diego)
Molecular model of KL001 (Image: Tsuyoshi Hirota, UC San Diego)
Scientists have long suspected that metabolic disorders, such as type 2 diabetes and obesity, could be linked to our circadian rhythm or biological clock. For example, laboratory mice with altered biological clocks often become obese and develop diabetes. Now biologists at UC San Diego have discovered that a chemical, which affects the activity of a key protein that regulates our biological clock, can repress the production of glucose by the liver, offering a promising new direction for the development of a new class of drugs to treat diabetes.
Other Images from this Gallery